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Antigens, CD27

More information in Books or onNLM PubMed
Definition: A member of the tumor necrosis factor receptor superfamily found on most T-LYMPHOCYTES. Activation of the receptor by CD70 ANTIGEN results in the increased proliferation of CD4-POSITIVE T-LYMPHOCYTES and CD8-POSITIVE T-LYMPHOCYTES. Signaling by the activated receptor occurs through its association with TNF RECEPTOR-ASSOCIATED FACTORS.      Other names Tumor Necrosis Factor Receptor Superfamily, Member; T-Cell Activation Antigen; CD27 Antigens; T Cell Activation Antigen; Receptor, TNFRSF7; CD27 Antigen; Antigen, T-Cell Activation; Activation Antigen, T-Cell; TNFRSF7 Receptor; Antigen, CD27
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Tnfsf4 protein, rat  0   *Membrane Glycoproteins *Tumor Necrosis Factors Ligands Antigens, CD27.
Tnfsf4 protein, mouse  0   *Membrane Glycoproteins *Tumor Necrosis Factors Ligands Antigens, CD27.
TNFSF4 protein, human  0   *OX40 Ligand Ligands Antigens, CD27. EMBO J 1994 Sep 1;13(17):3992-4001

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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