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Signal Recognition Particle

More information in Books or onNLM PubMed
Definition: A cytosolic ribonucleoprotein complex that acts to induce elongation arrest of nascent presecretory and membrane proteins until the ribosome becomes associated with the rough endoplasmic reticulum. It consists of a 7S RNA and at least six polypeptide subunits (relative molecular masses 9, 14, 19, 54, 68, and 72K).  DF: note short X ref   
See Also Protein Sorting Signals 		Other names SRP (Signal Recognition Particle); Recognition Particle, Signal; Particle, Signal Recognition
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
cpSRP43 protein, Arabidopsis  0   *Signal Recognition Particle *Arabidopsis Proteins Chloroplast Proteins. J Biol Chem. 2011 Oct 7;286(40):35187-95.
SRP68 protein, human  0   *Signal Recognition Particle Protein Subunits. Protein Sci 2006 Jun;15(6):1290-302
SRP72 protein, S cerevisiae  0   *Signal Recognition Particle *Saccharomyces cerevisiae Proteins.
Srp72 protein, mouse  0   *Signal Recognition Particle.
SRP72 protein, human  0   *Signal Recognition Particle.
SRP14 protein, human  0   *Signal Recognition Particle RNA-Binding Proteins.
Srp14 protein, mouse  0   *Signal Recognition Particle RNA-Binding Proteins.
SEC65 protein, S cerevisiae  0   *Signal Recognition Particle *Saccharomyces cerevisiae Proteins.
SRP9 protein, human  0   *Signal Recognition Particle.
SRP54 protein, human  0   *Signal Recognition Particle. Proc Natl Acad Sci U S A 2003 Dec 9;100(25):14701-6
SRP19 protein, human  0   *Signal Recognition Particle.
7SL RNA  0   *Signal Recognition Particle *RNA, Small Cytoplasmic.
Srp9 protein, mouse  0   *Signal Recognition Particle. EMBO J 1997 Jul 1;16(13):3757-66
SrpA protein, Aspergillus niger  0   *Fungal Proteins *Signal Recognition Particle. Gene 1995 Dec 29;167(1-2):337-8
srb protein, Bacillus subtilis  0   *Bacterial Proteins Receptors, Cytoplasmic and Nuclear Signal Recognition Particle. DNA Res 1995;2(2):95-100
nascent-polypeptide-associated complex  0   *Molecular Chaperones Signal Recognition Particle Protein Subunits. Proc Natl Acad Sci U S A 1995 Oct 10;92(21):9433-4
SRP21 protein, S cerevisiae  0   *Signal Recognition Particle *Saccharomyces cerevisiae Proteins. EMBO J 1994 Sep 15;13(18):4390-400
SRP14 protein, S cerevisiae  0   *Signal Recognition Particle *Saccharomyces cerevisiae Proteins. EMBO J 1994 Sep 15;13(18):4390-400
FFC protein, Arabidopsis  0   *Signal Recognition Particle *Arabidopsis Proteins *Chloroplast Proteins. J Biol Chem 1993 Oct 15;268(29):22175-80
Ffh protein, E coli  0   *Signal Recognition Particle *Escherichia coli Proteins.
SRP68 protein, S cerevisiae  0   *Signal Recognition Particle *Saccharomyces cerevisiae Proteins.
SRP54 protein, S cerevisiae  0   *Signal Recognition Particle *Saccharomyces cerevisiae Proteins. FEBS Lett 1991;283(2):325
signal peptide receptor  0   *Receptors, Peptide *Receptors, Cytoplasmic and Nuclear Signal Recognition Particle. J Cell Biol 1982;95(2)Pt 1:463

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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