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Homeodomain Proteins

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Definition: Proteins encoded by homeobox genes (GENES, HOMEOBOX) that exhibit structural similarity to certain prokaryotic and eukaryotic DNA-binding proteins. Homeodomain proteins are involved in the control of gene expression during morphogenesis and development (GENE EXPRESSION REGULATION, DEVELOPMENTAL).  DNA-binding proteins   
Examples Antennapedia Homeodomain Protein; Fushi Tarazu Transcription Factors; Goosecoid Protein; MADS Domain Proteins; MSX1 Transcription Factor; Onecut Transcription Factors; Otx Transcription Factors; PAX7 Transcription Factor 		Other names Homeoproteins; Homeobox Proteins; Proteins, Homeotic; Proteins, Homeodomain; Proteins, Homeobox; Proteins, Homeo Domain; Homeotic Proteins; Homeo Domain Proteins
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
VAX1 protein, human  0   *Transcription Factors *Homeodomain Proteins. Development. 2011 Mar;138(5):873-8.
PHF20 protein, mouse  0   *Homeodomain Proteins Zinc Fingers. J Biol Chem. 2012 Jan 2;287(1):429-37
Dlx3 protein, Xenopus  0   *Transcription Factors *Xenopus Proteins Homeodomain Proteins. Nucleic Acids Res. 1999 Feb 1;27(3):764-70.
TOPAZ1 protein, mouse  0   *Homeodomain Proteins. PLoS One. 2011;6(11):e26950
HB33 protein, Arabidopsis  0   *Homeodomain Proteins *Arabidopsis Proteins. PLoS Genet. 2011 Jul;7(7):e1002172.
rhinoceros protein, Drosophila  0   *Homeodomain Proteins *Drosophila Proteins Nuclear Proteins Zinc Fingers. Genetics. 2003 Dec;165(4):1993-2006.
HOMEZ protein, Xenopus  0   *Transcription Factors *Homeodomain Proteins *Xenopus Proteins Zinc Fingers Leucine Zippers. Biochem Biophys Res Commun. 2011 Nov 11;415(1):11-6
TSHZ1 protein, human  0   *Homeodomain Proteins Antigens, Neoplasm Zinc Fingers. Int J Oncol. 2011 Nov;39(5):1143-51.
SHH1 protein, Arabidopsis  0   *Homeodomain Proteins *Arabidopsis Proteins. PLoS Genet. 2011 Jul;7(7):e1002195.
WOX1 protein, Arabidopsis  0   *Homeodomain Proteins *Arabidopsis Proteins. J Integr Plant Biol. 2011 Jun;53(6):493-506.
irx3b protein, Danio rerio  0   *Transcription Factors *Homeodomain Proteins *Zebrafish Proteins. Dev Dyn. 2011 Aug;240(8);2011-27
CEH-23 protein, C elegans  0   *Homeodomain Proteins *Caenorhabditis elegans Proteins. Genetics 1998 Jan;148(1):151-65
Dbx2 protein, Xenopus  0   *Homeodomain Proteins *Xenopus Proteins. Biochem Biophys Res Commun 2011 Aug 19;412(1):170-4
PNF protein, Arabidopsis  0   *Homeodomain Proteins *Arabidopsis Proteins. Plant Physiol 2011 Jun;156(2):605-14
HOXC9 protein, zebrafish  0   *Homeodomain Proteins *Zebrafish Proteins Transcription Factors. Circ Res. 2011 May 27;108(11):1367-77
Hmx4 protein, zebrafish  0   *Homeodomain Proteins *Zebrafish Proteins. Dev Biol 2011 Jul 1;355(1):55-64
Hmbox1 protein, rat  0   *Homeodomain Proteins. ACS Chem Biol 2010 Nov 19;5(11):1035-43
Prep1.1 protein, zebrafish  0   *Transcription Factors *Zebrafish Proteins Homeodomain Proteins. PLoS One 2010;5(12):e15047
HOMEZ protein, human  0   *Transcription Factors *Homeodomain Proteins Zinc Fingers Leucine Zippers. PLoS One. 2010;5(4) (dup#6):e10286
EGAM1C protein, mouse  0   *Homeodomain Proteins. Reproduction. 2011 Feb;141(2):259-68
hybrid Antp-TPR peptide  0   *Homeodomain Proteins. J Transl Med 2011;9:8
ATHB8 protein, Arabidopsis  0   *Transcription Factors *Homeodomain Proteins *Arabidopsis Proteins. Int J Dev Biol. 2010;54(8-9):1389-96
Nkx6.1 protein, Xenopus  0   *Transcription Factors *Xenopus Proteins Homeodomain Proteins. Dev Biol 2011 Jan 15;349(2):378-86
Duxbl protein, mouse  0   *Transcription Factors *Homeodomain Proteins. Dev Dyn 2010 Mar;239(3):927-40
Pbx1 protein, zebrafish  0   *Transcription Factors *Zebrafish Proteins Homeodomain Proteins. Dev Dyn 2010 Mar;239(3):865-74
PRM-151  0   *Serum Amyloid P-Component *Homeodomain Proteins Recombinant Proteins. Drug News Perspect. 2010 Jun;23(5):305-15
NANOG2 protein, human  0   *Transcription Factors *Homeodomain Proteins. Nucleic Acids Res 2010 Sep;38(16):5384-95
PHF10 protein, human  0   *Neoplasm Proteins *Homeodomain Proteins Zinc Fingers. Mol Cancer Ther 2010 Jun;9(6):1764-74
BSX protein, rat  0   *Nerve Tissue Proteins *Transcription Factors Homeodomain Proteins. FASEB J 2010 Aug;24(8):2670-9
HMBX-1 protein, C elegans  0   *Transcription Factors *Caenorhabditis elegans Proteins Homeodomain Proteins. Genes Dev 2010 Aug 15;24(16):1802-15
pitchfork protein, mouse  0   *Homeodomain Proteins. Dev Cell 2010 Jul 20;19(1):66-77
Prep1.2 protein, zebrafish  0   *Transcription Factors *Zebrafish Proteins Homeodomain Proteins. Dev Biol 2010 Jul 1;343(1-2):94-103
CLP36 protein, mouse  0   *Homeodomain Proteins. Neurosci Lett. 2010 May 31;476(2):53-7
Hoxa3 protein, zebrafish  0   *Homeodomain Proteins *Zebrafish Proteins. Proc Natl Acad Sci U S A 2010 Jun 8;107(23):10555-60
HOXD12 protein, human  0   *Transcription Factors *Homeodomain Proteins. Brain Dev. 2010 May;32(5):356-61
HOXD8 protein, rat  0   *Transcription Factors *Homeodomain Proteins. J Microbiol Biotechnol. 2009 Dec;19(12):1557-64
Hmx3 protein, zebrafish  0   *Transcription Factors *Zebrafish Proteins Homeodomain Proteins. Dev Biol 2010 Mar 15;339(2):507-18
Hmx2 protein, zebrafish  0   *Transcription Factors *Zebrafish Proteins Homeodomain Proteins. Dev Biol 2010 Mar 15;339(2):507-18
Bsx protein, Xenopus  0   *Transcription Factors *Xenopus Proteins Homeodomain Proteins. Proc Natl Acad Sci U S A 2010 Apr 6;107(14):6352-7
HOXD13 protein, rat  0   *Transcription Factors *Homeodomain Proteins. Cytogenet Genome Res 2008;121(3-4):189-95
EN1 protein, rat  0   *Homeodomain Proteins. Yi Chuan. 2009 Dec;31(12):1214-20)
CrxOS protein, mouse  0   *Homeodomain Proteins. Biochem Biophys Res Commun 2009 Dec 25;390(4):1129-35
TDRG1 protein, human  0   *Homeodomain Proteins. Nan Fang Yi Ke Da Xue Xue Bao. 2009 Apr;29(4):631-4
Yox1 protein, S pombe  0   *Homeodomain Proteins *Schizosaccharomyces pombe Proteins. PLoS Genet 2009 Aug;5(8):e1000626
CEH-51 protein, C elegans  0   *Transcription Factors *Caenorhabditis elegans Proteins Homeodomain Proteins. Development 2009 Aug;136(16):2735-46
BLH3 protein, Arabidopsis  0   *Transcription Factors *Homeodomain Proteins. Biochimie. 2009 Aug;91(8):974-81
CEH-34 protein, C elegans  0   *Transcription Factors *Caenorhabditis elegans Proteins Homeodomain Proteins. Dev Biol 2009 Jul 15;331(2):350-60
CEH-16 protein, C elegans  0   *Transcription Factors *Caenorhabditis elegans Proteins Homeodomain Proteins. Dev Biol 2009 Sep 15;333(2):337-47
BLH1 protein, Arabidopsis  0   *Transcription Factors *Arabidopsis Proteins Homeodomain Proteins. Proc Natl Acad Sci U S A 2009 Aug 11;106(32):13624-9
Lmx1b protein, zebrafish  0   *Transcription Factors *Zebrafish Proteins Homeodomain Proteins. Dev Biol 2009 Aug 15;332(2):287-98
HoxB3 protein, human  0   *Homeodomain Proteins. Mol Biol Rep 2009 Feb;36(2):227-35
LBX1 protein, human  0   *Transcription Factors *Homeodomain Proteins. Genes Dev 2009 Aug 1;23(15):1737-42
BSX protein, human  0   *Homeodomain Proteins. Neurogenetics. 2009 Apr;10(2):89-95
Cdx2 protein, rat  0   *Transcription Factors *Homeodomain Proteins. Gut 2009 May;58(5):620-8
Lbx2 protein, zebrafish  0   *Repressor Proteins *Zebrafish Proteins Homeodomain Proteins. BMC Dev Biol 2009;9:13
Irx4a protein, zebrafish  0   *Transcription Factors *Zebrafish Proteins Homeodomain Proteins. Mol Cell Neurosci 2009 Mar;40(3):328-37
Rx-L protein, Xenopus  0   *Homeodomain Proteins *Xenopus Proteins Eye Proteins. Dev Biol 2009 Mar 15;327(2):352-65
Irx5 protein, rat  0   *Transcription Factors *Homeodomain Proteins. Cardiovasc Res 2009 Jan 1;81(1):64-71
Irx4 protein, rat  0   *Transcription Factors *Homeodomain Proteins. Cardiovasc Res 2009 Jan 1;81(1):64-71
Hoxa6 protein, human  0   *Homeodomain Proteins. Exp Hematol 2009 Mar;37(3):322-33.e3
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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