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Gene Dosage

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Definition: The number of copies of a given gene present in the cell of an organism. An increase in gene dosage (by GENE DUPLICATION for example) can result in higher levels of gene product formation. GENE DOSAGE COMPENSATION mechanisms result in adjustments to the level GENE EXPRESSION when there are changes or differences in gene dosage.  do not confuse with DOSAGE COMPENSATION, GENETIC   
See Also DNA Copy Number Variations
Examples Haploinsufficiency
Other names Numbers, Gene Copy; Number, Gene Copy; Gene Dosages; Gene Copy Numbers; Dosages, Gene; Copy Numbers, Gene; Copy Number, Gene; Dosage, Gene; Gene Copy Number

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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