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Nicotinic Antagonists

More information in Books or onNLM PubMed
Definition: Drugs that bind to nicotinic cholinergic receptors (RECEPTORS, NICOTINIC) and block the actions of acetylcholine or cholinergic agonists. Nicotinic antagonists block synaptic transmission at autonomic ganglia, the skeletal neuromuscular junction, and at central nervous system nicotinic synapses.  GEN or unspecified; prefer specifics; DF: NICOTINIC ANTAG    Other names Antagonists, Nicotinic
Substances having this pharmacologic action: 3-(trifluoromethyl)-3-(3-iodophenyl)diazirine; delta-philanthotoxin; 1-hexanol; Atracurium; Chlorisondamine; Alcuronium; Pipecuronium; Hexamethonium; Trimethaphan; Tubocurarine; Vecuronium Bromide; Toxiferine; Pancuronium; Pempidine; Pentolinium Tartrate; Mecamylamine; Gallamine Triethiodide; Curare; Ethidium; alpha-conotoxin MII; methyllycaconitine
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
3-(2-azetidinylmethoxy)-5-(3'-fluoropropyl)pyridine  0   *Azetidines *Pyridines Fluorine Radioisotopes Nicotinic Antagonists. Nucl Med Biol. 2011 Nov;38(8):1183-92.
alpha4 nicotinic acetylcholine receptor, Conus regius  0   *Receptors, Nicotinic *Conotoxins Nicotinic Antagonists. Biochem Pharmacol. 2012 Feb 1;83(3):419-26
gymnodimine A  0   *Heterocyclic Compounds with 4 or More Rings *Imines Marine Toxins Nicotinic Antagonists. Org Biomol Chem. 2011 Dec 7;9(23):8112-8

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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