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Molecular Chaperones

More information in Books or onNLM PubMed
Definition: A family of cellular proteins that mediate the correct assembly or disassembly of polypeptides and their associated ligands. Although they take part in the assembly process, molecular chaperones are not components of the final structures.  a class of proteins; GEN or unspecified; prefer specifics; DF: MOL CHAPERONES   
See Also Heat-Shock Proteins
Examples alpha-Crystallins; Clusterin; Heat-Shock Proteins; Histone Chaperones; Metallochaperones; Neuroendocrine Secretory Protein 7B2; SMN Complex Proteins
Other names Molecular Chaperone; Chaperone, Molecular; Chaperones, Molecular
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Tah1 protein, S cerevisiae  0   *Molecular Chaperones *Saccharomyces cerevisiae Proteins. Cell. 2005 Mar 11;120(5):715-27.
XPORT protein, Drosophila  0   *Molecular Chaperones *Drosophila Proteins. Neuron. 2011 Nov 17;72(4):602-15.
YcdY protein, E coli  0   *Molecular Chaperones *Escherichia coli Proteins. J Bacteriol. 2011 Dec;193(23):6512-6.
RbcX2 protein, Arabidopsis  0   *Molecular Chaperones *Arabidopsis Proteins Chloroplast Proteins. Plant Mol Biol. 2011 Nov;77(4-5):447-59.
RbcX1 protein, Arabidopsis  0   *Molecular Chaperones *Arabidopsis Proteins Chloroplast Proteins. Plant Mol Biol. 2011 Nov;77(4-5):447-59.
UXT protein, mouse  0   *Molecular Chaperones. Biochem Biophys Res Commun. 2011 Sep 30;413(3):471-5.
Hip3 protein, S pombe  0   *Molecular Chaperones *Schizosaccharomyces pombe Proteins. J Biol Chem 2006 Mar 31;281(13):8732-9
OEP61 protein, Arabidopsis  0   *Molecular Chaperones *Arabidopsis Proteins. Biochem J. 2011 Aug 15;438(1):143-53
Cj1289 protein, Campylobacter jejuni  0   *Bacterial Proteins *Virulence Factors Molecular Chaperones. J Biol Chem 2011 Jun 17;286(24):21254-65
Cj0596 protein, Campylobacter jejuni  0   *Bacterial Proteins *Virulence Factors Molecular Chaperones. J Biol Chem 2011 Jun 17;286(24):21254-65
PulS protein, E coli  0   *Molecular Chaperones *Escherichia coli Proteins. EMBO J 1996 Mar 1;15(5):978-88
DNLZ protein, human  0   *Molecular Chaperones Zinc Fingers. Biochem Biophys Res Commun 2011 May 20;408(4):589-94
ArsD protein, E coli  0   *Molecular Chaperones *Escherichia coli Proteins. Mol Microbiol 1993 May;8(3):615-23
Mss4 protein, human  0   *Molecular Chaperones. Biol Chem 2011 Mar;392(3):239-48
FOXRED1 protein, human  0   *Molecular Chaperones. Hum Mol Genet 2010 Dec 15;19(24):4837-47
ANKRD13C protein, human  0   *Membrane Proteins *Molecular Chaperones Ankyrin Repeat. J Biol Chem 2010 Dec 24;285(52):40838-51
tubulin-folding cofactor A, Arabidopsis  0   *Molecular Chaperones *Arabidopsis Proteins. Acta Crystallogr Sect F Struct Biol Cryst Commun 2010 Aug 1;66(Pt 8):954-6
UNC-45 protein, Drosophila  0   *Molecular Chaperones *Drosophila Proteins. Biochem Biophys Res Commun 2010 May 28;396(2):317-22
TFC-B protein, Arabidopsis  0   *Molecular Chaperones *Arabidopsis Proteins. Front Biosci (Elite Ed) 2010;2:752-63
fls485 protein, human  0   *Molecular Chaperones. BMC Gastroenterol. 2010;10() (dup#19):27
FKBP53 protein, Arabidopsis  0   *Molecular Chaperones *Tacrolimus Binding Proteins *Arabidopsis Proteins. Cell Res. 2010 Mar;20(3):357-66
StpA protein, Salmonella typhimurium  0   *Bacterial Proteins *DNA-Binding Proteins *Molecular Chaperones. Mol Microbiol. 2009 Dec;74(5):1169-86
PRKCSH protein, zebrafish  0   *Molecular Chaperones *Zebrafish Proteins. Hum Mol Genet 2010 Jan 1;19(1):16-24
pERp1 protein, mouse  0   *Molecular Chaperones. Proc Natl Acad Sci U S A 2009 Oct 6;106(40):17013-8
Cwc23 protein, S cerevisiae  0   *Molecular Chaperones *Saccharomyces cerevisiae Proteins. Mol Cell Biol 2010 Jan;30(1):33-42
glycoprotein 93, Drosophila  0   *Molecular Chaperones *Drosophila Proteins Glycoproteins. J Immunol 2009 Oct 15;183(8):5121-8
Ric-3 protein, mouse  0   *Membrane Proteins *Molecular Chaperones. J Neurosci 2009 Oct 7;29(40):12625-35
HybE protein, E coli  0   *Molecular Chaperones *Escherichia coli Proteins. Biomol NMR Assign. 2009 Jun;3(1):129-31
Jid1 protein, S cerevisiae  0   *Molecular Chaperones *Saccharomyces cerevisiae Proteins Mitochondrial Proteins. FEBS Lett 2009 Sep 3;583(17):2954-8
CSP3 protein, Arabidopsis  0   *Heat-Shock Proteins *Arabidopsis Proteins Molecular Chaperones. J Biol Chem 2009 Aug 28;284(35):23454-60
sacsin protein, rat  0   *Molecular Chaperones. Hum Mol Genet 2009 May 1;18(9):1556-65
tubulin-specific chaperone E, Drosophila  0   *Molecular Chaperones. Development 2009 May;136(9):1571-81
HBP21 protein, human  0   *Molecular Chaperones. Mol Biotechnol 2008 Nov;40(3):231-40
Sgt1 protein, Drosophila  0   *Molecular Chaperones *Drosophila Proteins. EMBO J 2009 Feb 4;28(3):234-47
Bag2 protein, mouse  0   *Molecular Chaperones *Adaptor Proteins, Signal Transducing. Nat Struct Mol Biol 2008 Dec;15(12):1309-17
prefoldin 6 protein, Arabidopsis  0   *Molecular Chaperones *Arabidopsis Proteins. Proc Natl Acad Sci U S A 2008 Nov 18;105(46):18064-9
Rtp4 protein, mouse  0   *Molecular Chaperones. Proc Natl Acad Sci U S A 2008 Oct 14;105(41):16045-50
Ypr158 protein, S cerevisiae  0   *Molecular Chaperones *Saccharomyces cerevisiae Proteins. EMBO J 2008 Oct 22;27(20):2725-35
Nap2 protein, S pombe  0   *Molecular Chaperones *Schizosaccharomyces pombe Proteins. Biochim Biophys Acta 2008 Sep;1783(9):1595-604
Nap1 protein, S pombe  0   *Molecular Chaperones *Schizosaccharomyces pombe Proteins. Biochim Biophys Acta 2008 Sep;1783(9):1595-604
ERdj5 protein, mouse  0   *Molecular Chaperones *HSP40 Heat-Shock Proteins. Science. 2008 Jul 25;321(5888):499-500
ASF1 protein, C elegans  0   *Molecular Chaperones *Caenorhabditis elegans Proteins. Dev Biol 2008 Jul 1;319(1):100-9
Unc45a protein, zebrafish  0   *Molecular Chaperones *Zebrafish Proteins. Dev Biol 2008 Jun 15;318(2):258-67
Unc45b protein, zebrafish  0   *Molecular Chaperones *Zebrafish Proteins. J Cell Biol 2008 Mar 24;180(6):1163-75
Dmp2 protein, S cerevisiae  0   *Molecular Chaperones *Saccharomyces cerevisiae Proteins Protein Subunits. Nat Struct Mol Biol 2008 Mar;15(3):228-36
Dmp1 protein, S cerevisiae  0   *Molecular Chaperones *Saccharomyces cerevisiae Proteins Protein Subunits. Nat Struct Mol Biol 2008 Mar;15(3):228-36
Vps75 protein, S cerevisiae  0   *Molecular Chaperones *Saccharomyces cerevisiae Proteins. Arch Biochem Biophys 2008 Jan 15;469(2):157-64
ASF1 protein, S pombe  0   *Molecular Chaperones *Schizosaccharomyces pombe Proteins. J Biol Chem Sep 28;292(39):28587-96
ROT1 protein, S cerevisiae  0   *Membrane Proteins *Molecular Chaperones *Saccharomyces cerevisiae Proteins. J Biochem (Tokyo) 2006 Mar;139(3):597-605
RbcX protein, cyanobacteria  0   *Bacterial Proteins *Molecular Chaperones. Cell 2007 Jun 15;129(6):1189-200
ERp44 protein, mouse  0   *Membrane Proteins *Molecular Chaperones. Mol Cell Biol 2007 May;27(10):3716-31
Cox19 protein, S cerevisiae  0   *Molecular Chaperones *Saccharomyces cerevisiae Proteins. J Biol Chem 2007 Apr 6;282(14):10233-42
BCS1L protein, mouse  0   *Molecular Chaperones. Gene Expr Patterns 2007 Jan;7(3):266-73
NRP2 protein, Arabidopsis  0   *Molecular Chaperones *Arabidopsis Proteins. Plant Cell 2006 Nov;18(11):2879-92
NRP1 protein, Arabidopsis  0   *Molecular Chaperones *Arabidopsis Proteins. Plant Cell 2006 Nov;18(11):2879-92
dMRJ protein, Drosophila  0   *Molecular Chaperones *Drosophila Proteins. Neurobiol Dis 2006 Nov;24(2):226-44
AHSA1 protein, human  0   *Molecular Chaperones. Cell 2006 Nov 17;127(4):803-15
PKR1 protein, S cerevisiae  0   *Membrane Proteins *Molecular Chaperones *Saccharomyces cerevisiae Proteins. J Biol Chem 2006 Oct 20;281(42):32025-35
CDC-37 protein, C elegans  0   *Cell Cycle Proteins *Caenorhabditis elegans Proteins Molecular Chaperones. Development 2006 Oct;133(19):3745-54
Cosmc protein, mouse  0   *Molecular Chaperones. Science. 2006 Oct 13;314(5797):304-8
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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