Neural Cell Adhesion Molecules (definition)

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Neural Cell Adhesion Molecules

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Definition: Cell adhesion molecule involved in a diverse range of contact-mediated interactions among neurons, astrocytes, oligodendrocytes, and myotubes. It is widely but transiently expressed in many tissues early in embryogenesis. Four main isoforms exist, including CD56; (ANTIGENS, CD56); but there are many other variants resulting from alternative splicing and post-translational modifications. (From Pigott & Power, The Adhesion Molecule FactsBook, 1993, pp115-119)

NCAM: note X ref NEURAL CELL ADHESION MOLECULE but do not confuse this X ref with NEURONAL CELL ADHESION MOLECULES see CELL ADHESION MOLECULES, NEURONAL
Examples Antigens, CD56; Neural Cell Adhesion Molecule L1; Neurocan

Other names Cell Adhesion Molecules, Neural; Neural Cell Adhesion Molecule; NCAM; Cell Adhesion Molecule, Neural

Substance	Categories	Source
MDGA2 protein, mouse	Neural Cell Adhesion Molecules GPI-Linked Proteins.	Biochem Biophys Res Commun. 2012 Feb 17;418(3):439-44
gliomedin protein, human	*Neural Cell Adhesion Molecules.	Neuron. 2005 Jul 21;47(2):215-29.
LRRTM2 protein, mouse	*Neural Cell Adhesion Molecules.	J Cell Biol 2011 Jul 25;194(2):323-34
LRRTM1 protein, mouse	*Neural Cell Adhesion Molecules.	J Cell Biol 2011 Jul 25;194(2):323-34
NGL-3 protein, rat	*Neural Cell Adhesion Molecules.	J Biol Chem 2010 Apr 30;285(18):13966-78
LRRTM2 protein, rat	*Neural Cell Adhesion Molecules.	Neuron 2009 Dec 24;64(6):799-806
MDGA2 protein, human	Neural Cell Adhesion Molecules GPI-Linked Proteins.	Psychiatr Genet. 2009 Aug;19(4):213-4
Nrxn1 protein, mouse	*Neural Cell Adhesion Molecules.	Nat Struct Mol Biol 2008 Jan;15(1):50-6
Dscam2 protein, Drosophila	Neural Cell Adhesion Molecules Drosophila Proteins.	Nature 2007 Jun 7;447(7145):720-4
Ncam2 protein, rat	*Neural Cell Adhesion Molecules.
SAX-7 protein, C elegans	Neural Cell Adhesion Molecules Caenorhabditis elegans Proteins.	EMBO J 2005 Apr 6;24(7):1477-88
PLXNB3 protein, human	Nerve Tissue Proteins Neural Cell Adhesion Molecules.	EMBO Rep 2004 Jul;5(7):710-4
NCAM protein (681-695), human	*Neural Cell Adhesion Molecules.	J Neurosci 2004 Apr 28;24(17):4197-204
DRAGON protein, mouse	Nerve Tissue Proteins Neural Cell Adhesion Molecules.	J Neurosci 2004 Feb 25;24(8):2027-36
ncam3 protein, zebrafish	Neural Cell Adhesion Molecules Zebrafish Proteins.	Mol Cell Neurosci 2001 Jul;18(1):119-30
ncam2 protein, zebrafish	Neural Cell Adhesion Molecules Zebrafish Proteins.	Mol Cell Neurosci 2001 Jul;18(1):119-30
NCAM1 protein, zebrafish	Neural Cell Adhesion Molecules Zebrafish Proteins.	Mol Cell Neurosci 2001 Jul;18(1):119-30
SIRPB2 protein, human	*Neural Cell Adhesion Molecules.	J Hum Genet 2000;45(6):378-82
Ncam2 protein, mouse	*Neural Cell Adhesion Molecules.	J Biol Chem 1997 Oct 17;272(42):26083-6
sidekick protein, Drosophila	Eye Proteins Neural Cell Adhesion Molecules *Drosophila Proteins Immunoglobulins.	Development 1997 Sep;124(17):3303-12
neurotrimin	*Neural Cell Adhesion Molecules GPI-Linked Proteins Immunoglobulins.	J Neurosci 1995 Mar;15(3 Pt 2):2141-56
cell adhesion molecule F11	*Neural Cell Adhesion Molecules.	Neuron 1993 Jan;10(1):69-82
neural cell surface antigen BSP-2	*Sialic Acids Neural Cell Adhesion Molecules.	Nature 1983;304(5924):347

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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