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Tight Junctions

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Definition: Cell-cell junctions that seal adjacent epithelial cells together, preventing the passage of most dissolved molecules from one side of the epithelial sheet to the other. (Alberts et al., Molecular Biology of the Cell, 2nd ed, p22)      Other names Zonula Occluden; Tight Junction; Occluding Junction; Occludens, Zonula; Occluden, Zonula; Junctions, Tight; Junctions, Occluding; Junction, Tight; Junction, Occluding; Zonula Occludens; Occluding Junctions
 
SubstanceCAS Registry & nameCategoriesSource
cldn5a protein, zebrafish  0   *Zebrafish Proteins *Claudins Tight Junctions. Proc Natl Acad Sci U S A 2010 Jan 26;107(4):1425-30
AmotL1 protein, zebrafish  0   *Zebrafish Proteins Pseudopodia Tight Junctions. Circ Res 2009 Jul 31;105(3):260-70
NHS protein, mouse  0   *Carrier Proteins Eye Proteins Tight Junctions. Exp Cell Res 2009 Aug 15;315(14):2358-72
Rab13 protein, rat  EC 3.6.1.-   *GTP Phosphohydrolases Tight Junctions. Biol Reprod 2009 Mar;80(3):590-601
TJP2 protein, zebrafish  0   *Membrane Proteins *Zebrafish Proteins Tight Junctions. Gene Expr Patterns 2007 Aug;7(7):767-76
MARVELD2 protein, human  0   *Membrane Proteins Tight Junctions. Am J Hum Genet 2006 Dec;79(6):1040-51
PARD3 protein, human  0   *Membrane Proteins *Cell Cycle Proteins Tight Junctions. Gene 2002 Jul 10;294(1-2):99-107
Cld19 protein, rat  0   *Claudins Tight Junctions. FEBS Lett 2006 Feb 6;580(3):923-31
claudin 16  0   *Claudins Tight Junctions.
LYRIC protein, rat  0   *Carrier Proteins Tight Junctions. Exp Cell Res 2004 Oct 15;300(1):134-48
Magi1 protein, mouse  0   *Membrane Proteins *Adaptor Proteins, Signal Transducing Tight Junctions. Exp Cell Res 2004 Oct 15;300(1):121-33
CRB3 protein, human  0   *Membrane Glycoproteins Tight Junctions. Gene 2003 Jan 2;302(1-2):21-9
PARD3B protein, human  0   *Carrier Proteins *Membrane Proteins Tight Junctions. Gene 2002 Jul 10;294(1-2):99-107
TJAP1 protein, human  0   *Membrane Proteins Tight Junctions. J Biol Chem 2001 Dec 21;276(51):48350-5
junctional adhesion molecule  0   *Cell Adhesion Molecules Antigens Immunoglobulins Tight Junctions. J Cell Biol 1998 Jul 13;142(1):117-27
claudin 1  0   *Membrane Proteins Tight Junctions. J Cell Biol 1998 Jun 29;141(7):1539-50
SYMPK protein, human  0   *Nuclear Proteins Tight Junctions. J Cell Biol 1996 Aug;134(4):1003-18
zonula occludens-2 protein  0   *Membrane Proteins Tight Junctions. J Cell Biol 1994 Mar;124(6):949-61

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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