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N-Acetylneuraminic Acid

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Definition: An N-acyl derivative of neuraminic acid. N-acetylneuraminic acid occurs in many polysaccharides, glycoproteins, and glycolipids in animals and bacteria. (From Dorland, 28th ed, p1518)  do not confuse with N-ACETYLNEURAMINIC ACIDS see SIALIC ACIDS; do not confuse X ref SIALIC ACID with SIALIC ACIDS    Other names N Acetylneuraminic Acid; Acid, Sialic; Acid, N-Acetylneuraminic; Sialic Acid
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
N-acetyl-2,3-dehydro-2-deoxyneuraminic acid  0   N-Acetylneuraminic Acid/*analogs & derivatives Neuraminidase/antagonists & inhibitors. Eur J Neurosci 2010 Dec;32(11):1889-96
2,3-didehydro-N-acetyl-neuraminic acid  0   N-Acetylneuraminic Acid/*analogs & derivatives. Bioorg Med Chem Lett. 2010 Dec 15;20(24):7529-33
4-amido-N5-acetyl-4-deoxyneuraminic acid  0   N-Acetylneuraminic Acid/*analogs & derivatives. Org Lett. 2009 Aug 20;11(16):3678-81
methyl 5-acetamido-9-O-acetyl-2,6-anhydro-4-azido-3,4,5-trideoxy-glycero-galacto-non-2-enoic acid  0   N-Acetylneuraminic Acid/*analogs & derivatives. Carbohydr Res 2008 Sep;343(14):2459-62
methyl 5-N-acetyl-7-O-acetyl-4-azido-2,3-didehydro-2,4-dideoxyneuraminic acid  0   N-Acetylneuraminic Acid/*analogs & derivatives. Carbohydr Res 2008 Sep;343(14):2459-62
2'-(4-methylumbelliferyl)-N-acetylneuraminic acid-alpha2,3-galactose  0   *Galactosides Hymecromone/*analogs & derivatives N-Acetylneuraminic Acid/*analogs & derivatives. Anal Biochem 2003 Nov 15;322(2):139-47
2,3-didehydro-2,7-dideoxy-N-acetylneuraminic acid.  0   N-Acetylneuraminic Acid/*analogs & derivatives. Carbohydr Res. 2002 Nov 19;337(21-23):1917-27
O-acetyl sialic acid  0   N-Acetylneuraminic Acid. Glycoconj J 2001 Jul;18(7):529-37
4,9-diamino-2-deoxy-2,3-didehydro-N-acetylneuraminic  0   N-Acetylneuraminic Acid/*analogs & derivatives. Protein Sci 2001 Apr;10(4):689-96
9-amino-2-deoxy-2,3-didehydro-N-acetylneuraminic  0   N-Acetylneuraminic Acid/*analogs & derivatives. Protein Sci 2001 Apr;10(4):689-96
(2,2-bis(docosyloxymethyl)propyl-5-acetamido-3,5-dideoxy-4,7,8,9-tetra-O-(sodium oxysulfonyl)glycero-alpha-galacto-2-nonulopyranosid)onate  0   *Lipids N-Acetylneuraminic Acid/*analogs & derivatives. Antiviral Res 2000 Jul;47(1):41-51
5-bromo-4-chloro-3-indolyl-N-acetylneuraminic acid  0   N-Acetylneuraminic Acid/*analogs & derivatives. J Clin Microbiol 2000 Aug;38(8):3096-7
uridine monophosphate N-acetylneuraminic acid  0   Uridine Monophosphate/*analogs & derivatives N-Acetylneuraminic Acid/*analogs & derivatives. Biochemistry 2000 Mar 7;39(9) 2261-8
5-bromoindolyl-4,7-di-O-methyl-N-acetylneuraminic acid  0   N-Acetylneuraminic Acid/*analogs & derivatives. Carbohydr Res 1999 Apr 30;317(1-4):
CMP-(5-acetamido-9-thiomethylmercuric-3,5,9-trideoxy-D-glycero-D-galacto-nonulopyranosidonicacid)  0   *Cytidine Monophosphate *Mercury N-Acetylneuraminic Acid/*analogs & derivatives. Bioorg Med Chem 1998 Aug;6(8):1283-92
5-acetamido-9-thiomethylmercuric-3,5,9-trideoxy-D-glycero-D-galacto-nonulopyranosidonic acid  0   *Mercury N-Acetylneuraminic Acid/*analogs & derivatives. Bioorg Med Chem 1998 Aug;6(8):1283-92
N-acetyl-9-deoxyneuraminic acid  117193-36-9   N-Acetylneuraminic Acid/*analogs & derivatives. Carbohydr Res 1989;194:49
N-acetyl-8-deoxyneuraminic acid  117247-24-2   N-Acetylneuraminic Acid/*analogs & derivatives. Carbohydr Res 1989;194:49
N-acetyl-7-deoxyneuraminic acid  117193-31-4   N-Acetylneuraminic Acid/*analogs & derivatives. Carbohydr Res 1989;194:49
N-acetyl-4,7-dideoxyneuraminic acid  117193-44-9   N-Acetylneuraminic Acid/*analogs & derivatives. Carbohydr Res 1989;194:49
lipid-associated sialic acid  0   *Lipids *N-Acetylneuraminic Acid Tumor Markers, Biological. Clin Otolaryngol 1987;12(4):303
4,8-anhydro-N-acetylneuraminic acid  109915-63-1   N-Acetylneuraminic Acid/*analogs & derivatives. Eur J Biochem 1987;162(2):445
2,7-anhydro-N-acetylneuraminic acid  95574-95-1   N-Acetylneuraminic Acid/*analogs & derivatives. J Biochem (Tokyo) 1985;97(2):509
2-deoxy-2,3-dehydro-N-acetylneuraminic acid  24967-27-9 D-glycero-D-galacto-Non-2-enonic acid, 5-(acetylamino)-2,6-anhydro-3,5-dideoxy  N-Acetylneuraminic Acid/*analogs & derivatives Neuraminidase/antagonists & inhibitors.
Pharma Action Enzyme Inhibitors 		Eur J Biochem 1982;126(3):543
2,3-dehydro-4-epi-N-acetylneuraminic acid  79026-37-2 D-glycero-D-talo-Non-2-enonic acid, 5-(acetylamino)-2,6-anhydro-3,5-dideoxy  N-Acetylneuraminic Acid/*analogs & derivatives. Carbohydr Res 1981;94(2):123

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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