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GTP-Binding Proteins

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Definition: Regulatory proteins that act as molecular switches. They control a wide range of biological processes including: receptor signaling, intracellular signal transduction pathways, and protein synthesis. Their activity is regulated by factors that control their ability to bind to and hydrolyze GTP to GDP. EC 3.6.1.-.  GEN or unspecified; prefer specifics; GTP stands for Guanosine TriPhosphate   
Examples GTP Phosphohydrolase-Linked Elongation Factors; Heterotrimeric GTP-Binding Proteins; Monomeric GTP-Binding Proteins; Septins 		Other names Proteins, GTP-Regulatory; Proteins, GTP-Binding; Protein, GTP-Regulatory; Protein, GTP-Binding; GTP Regulatory Proteins; GTP Regulatory Protein; GTP Binding Proteins; GTP Binding Protein; G Proteins; G Protein; Guanine Nucleotide Coupling Protein; GTP-Regulatory Protein; GTP-Binding Protein; G-Protein; Guanine Nucleotide Regulatory Proteins; GTP-Regulatory Proteins; G-Proteins
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
NSN1 protein, Arabidopsis  EC 3.6.1.-   *GTP-Binding Proteins *Arabidopsis Proteins. Plant Mol Biol. 2012 Jan;78(1-2):31-44.
nucleostemin 2 protein, Drosophila  EC 3.6.1.-   *GTP-Binding Proteins *Drosophila Proteins. Biosci Biotechnol Biochem. 2011;75(8):1511-5.
ARF72A protein, Drosophila protein  EC 3.6.1.-   *GTP-Binding Proteins *Drosophila Proteins. J Cell Sci. 2006 Aug 15;119(Pt 16):3399-412.
Rab3-interacting molecule 1, human  0   *GTP-Binding Proteins. J Biol Chem. 2011 May 6;286(18):15757-65
ERAL1 protein, human  EC 3.6.1.-   *RNA-Binding Proteins *GTP-Binding Proteins Mitochondrial Proteins. Biochem J 2010 Aug 27;430(3):551-8
BPG2 protein, Arabidopsis  EC 3.6.1.-   *GTP-Binding Proteins *Arabidopsis Proteins Zinc Fingers. Plant J 2010 Feb 1;61(3):409-22
RACK1 protein, rat  0   *GTP-Binding Proteins. J Biol Chem 2010 Jun 18;285(25):19043-50
nucleostemin 1, Drosophila  EC 3.6.1.-   *GTP-Binding Proteins *Drosophila Proteins. Mol Biol Cell 2009 Oct;20(20):4424-34
Gng2 protein, rat  0   *GTP-Binding Proteins. Cereb Cortex. 2009 Oct;19(10):2372-9
EngA protein, E coli  EC 3.6.1.-   *GTP-Binding Proteins *Escherichia coli Proteins. Nucleic Acids Res 2009 Apr;37(7):2359-70
GNL1 protein, human  0   *GTP-Binding Proteins.
Era protein, mouse  0   *RNA-Binding Proteins *GTP-Binding Proteins. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 2005 May;21(3):280-3
DRP2B protein, Arabidopsis  EC 3.6.1.-   *GTP-Binding Proteins *Arabidopsis Proteins Cytoskeletal Proteins. Plant Cell Rep 2008 Oct;27(10):1581-6
HflX protein, E coli  EC 3.6.1.-   *GTP-Binding Proteins *Escherichia coli Proteins. Proc Natl Acad Sci U S A 1993 Nov 15;90(22):10866-70
GTG2 protein, Arabidopsis  EC 3.6.1.-   *Arabidopsis Proteins *Receptors, G-Protein-Coupled GTP-Binding Proteins. Cell 2009 Jan 9;136(1):136-48
GTG1 protein, Arabidopsis  EC 3.6.1.-   *Arabidopsis Proteins *Receptors, G-Protein-Coupled GTP-Binding Proteins. Cell 2009 Jan 9;136(1):136-48
GBP2 protein, human  EC 3.6.1.-   *GTP-Binding Proteins Tumor Markers, Biological. Int J Cancer 2009 Jan 15;124(2):272-9
Gbp45 protein, human  EC 3.6.1.-   *GTP-Binding Proteins. Cell Mol Biol Lett 2008;13(4):570-84
mAtNOS1 protein, human  EC 3.6.1.-   *GTP-Binding Proteins *Apoptosis Regulatory Proteins Mitochondrial Proteins. Biochim Biophys Acta 2008 Jun;1780(6):921-6
GBP5 protein, human  0   *GTP-Binding Proteins. J Infect Dis 2008 Mar 1;197(5):663-6
Ghalpha protein, rat  0   *Transglutaminases *GTP-Binding Proteins Intracellular Signaling Peptides and Proteins. Science 1994 Jun 10;264(5165):1593-6
Gbp8 protein, mouse  EC 3.6.1.-   *GTP-Binding Proteins. J Immunol 2007 Dec 1;179(11):7729-40
Gbp6 protein, mouse  EC 3.6.1.-   *GTP-Binding Proteins. J Immunol 2007 Dec 1;179(11):7729-40
GNL3L protein, mouse  0   *Nuclear Proteins *GTP-Binding Proteins. J Cell Sci. 2007 Aug 1;120(Pt 15):2532-43
OLA1 protein, human  EC 3.6.3.-   *Adenosine Triphosphatases *GTP-Binding Proteins. J Biol Chem 2007 Jul 6;282(27):19928-37
Gimap4 protein, rat  EC 3.6.1.-   *GTP-Binding Proteins. Diabetes 2002 Jun;51(6):1972-9
GIMAP7 protein, human  0   *GTP-Binding Proteins.
XGB protein, Xenopus  EC 3.6.1.-   *GTP-Binding Proteins *Xenopus Proteins Nuclear Proteins. Dev Growth Differ 2006 Dec;48(9):575-85
Der protein, E coli  EC 3.6.1.-   *GTP-Binding Proteins *Escherichia coli Proteins. Mol Microbiol 2006 Sep;61(6):1660-72
IRGM protein, human  EC 3.6.1.-   *GTP-Binding Proteins. Science. 2006 Sep 8;313(5792):1438-41
Atl1 protein, rat  EC 3.6.1.-   *DNA-Binding Proteins *GTP-Binding Proteins. Hum Mol Genet 2006 Apr 15;15(8):1343-53
Rop4 protein, Arabidopsis  EC 3.6.1.-   *GTP-Binding Proteins *Arabidopsis Proteins. Plant Physiol 1998 Oct;118(2):407-17
GNL3L protein, human  0   *GTP-Binding Proteins *Nuclear Proteins. Mol Biol Cell 2006 Jan;17(1):460-74
hypersensitive response-assisting protein, Arabidopsis  0   *GTP-Binding Proteins *Arabidopsis Proteins. Plant Mol Biol. 2005 Nov;59(5):771-80
RHO4 protein, S pombe  0   *GTP-Binding Proteins *Schizosaccharomyces pombe Proteins. Eukaryot Cell 2005 Oct;4(10):1639-45
SAR protein, human  EC 3.6.1.-   *GTP-Binding Proteins. Blood 2005 Nov 1;106(9):3256-63
DRP1 protein, Drosophila  EC 3.6.1.-   *Cytoskeletal Proteins *GTP-Binding Proteins. Neuron 2005 Aug 4;47(3):365-78
ROP1 protein, Arabidopsis  EC 3.6.1.-   *GTP-Binding Proteins *Arabidopsis Proteins. J Cell Biol 2005 Apr 11;169(1):127-38
Spn4 protein, S pombe  EC 3.6.1.-   *GTP-Binding Proteins *Schizosaccharomyces pombe Proteins. Mol Biol Cell 2004 Dec;15(12):5551-64
Spn3 protein, S pombe  EC 3.6.1.-   *GTP-Binding Proteins *Schizosaccharomyces pombe Proteins. Mol Biol Cell 2004 Dec;15(12):5551-64
Spn2 protein, S pombe  EC 3.6.1.-   *GTP-Binding Proteins *Schizosaccharomyces pombe Proteins. Mol Biol Cell 2004 Dec;15(12):5551-64
Spn1 protein, S pombe  EC 3.6.1.-   *GTP-Binding Proteins *Schizosaccharomyces pombe Proteins. Mol Biol Cell 2004 Dec;15(12):5551-64
ROP2 protein, Arabidopsis  EC 3.6.1.-   *GTP-Binding Proteins *Arabidopsis Proteins. Cell. 2005 Mar 11;120(5):687-700
GTPBP3 protein, human  EC 3.6.1.-   *GTP-Binding Proteins.
GTPBP4 protein, human  EC 3.6.1.-   *Nuclear Proteins *GTP-Binding Proteins Kidney Failure, Chronic.
Gtpbp4 protein, rat  EC 3.6.1.-   *Nuclear Proteins *GTP-Binding Proteins Kidney Failure, Chronic.
Trim23 protein, rat  0   *GTP-Binding Proteins.
RHOBTB2 protein, human  0   *GTP-Binding Proteins *Tumor Suppressor Proteins. Proc Natl Acad Sci U S A 2002 Oct 15;99(21):13647-52
Gimap5 protein, rat  EC 3.6.1.-   *GTP-Binding Proteins. Gene 2004 Oct 27;341:141-8
OpgG protein, E coli  0   *GTP-Binding Proteins *Escherichia coli Proteins. J Mol Biol 2004 Sep 3;342(1):195-205
rab11 binding protein, rat  0   *GTP-Binding Proteins.
RIMS1 protein, human  0   *Nerve Tissue Proteins *GTP-Binding Proteins.
Rims2 protein, mouse  0   *Nerve Tissue Proteins *GTP-Binding Proteins.
Rims1 protein, mouse  0   *GTP-Binding Proteins.
Rim1 protein, rat  0   *GTP-Binding Proteins.
Toc90 protein, Arabidopsis  0   *GTP-Binding Proteins *Arabidopsis Proteins. Plant Mol Biol 2004 Feb;54(3):427-40
HypB protein, E coli  0   *GTP-Binding Proteins *Escherichia coli Proteins Nickel.
Gbp1 protein, mouse  0   *GTP-Binding Proteins.
GBP1 protein, human  0   *GTP-Binding Proteins.
EXOC6B protein, human  0   *GTP-Binding Proteins.
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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