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BRCA1 Protein

More information in Books or onNLM PubMed
Definition: The phosphoprotein encoded by the BRCA1 gene (GENE, BRCA1). In normal cells the BRCA1 protein is localized in the nucleus, whereas in the majority of breast cancer cell lines and in malignant pleural effusions from breast cancer patients, it is localized mainly in the cytoplasm. (Science 1995;270(5237):713,789-91)     
See Also Genes, BRCA1; Hereditary Breast and Ovarian Cancer Syndrome 		Other names Breast Cancer 1 Protein; Breast Cancer 1 Gene Product; BRCA1 Gene Product
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
BRCA1 protein, human  0   *BRCA1 Protein. Nat Cell Biol 2004 Oct;6(10):954-67
BRCA1 protein, chicken  0   *Avian Proteins *BRCA1 Protein. Oncogene 2001 Jul 19;20(32):4433-8
BRCA1-delta11b  0   *BRCA1 Protein. Oncogene 1997 Jan 9;14(1):1-16

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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