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Nitroarginine

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Definition: An inhibitor of nitric oxide synthetase which has been shown to prevent glutamate toxicity. Nitroarginine has been experimentally tested for its ability to prevent ammonia toxicity and ammonia-induced alterations in brain energy and ammonia metabolites. (Neurochem Res 1995:200(4):451-6)  an enzyme inhib   
Pharmacological Action Enzyme Inhibitors
Other names omega-Nitro-L-Arginine, N; omega Nitroarginine; NG Nitroarginine; NG Nitro L Arginine; N omega Nitro L Arginine; omega-Nitroarginine; N(omega)-Nitroarginine; N(G)-Nitroarginine; NO2Arg; NOARG; NG-Nitroarginine; NG-Nitro-L-Arginine; N omega-Nitro-L-Arginine
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Re-imidazole-(CH2)8-nitroarginine  0   *Organometallic Compounds Nitroarginine/*analogs & derivatives. J Phys Chem B 2007 Jun 21;111(24):6628-33
N(alpha)-vanillyl-N(omega)-nitroarginine  0   Nitroarginine/*analogs & derivatives. Free Radic Res 2006 Jul;40(7):685-95
N(omega)-nitroarginine-2,4-diaminobutryic amide  0   Nitroarginine Nitric Oxide Synthase. J Med Chem 1999 Aug 12;42(16):3147-53

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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