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Teriparatide

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Definition: A polypeptide that consists of the 1-34 amino-acid fragment of human PARATHYROID HORMONE, the biologically active N-terminal region. The acetate form is given by intravenous infusion in the differential diagnosis of HYPOPARATHYROIDISM and PSEUDOHYPOPARATHYROIDISM. (Reynolds JEF(Ed): Martindale: The Extra Pharmacopoeia (electronic version). Micromedex, Inc, Englewood, CO, 1995)     
Pharmacological Action Bone Density Conservation Agents 		Other names Teriparatide Lilly Brand; Teriparatide Aventis Brand; Teriparatide Acetate; Parathar; Lilly Brand of Teriparatide; Forteo; Aventis Brand of Teriparatide; hPTH (1-34); Human Parathyroid Hormone (1-34)Drugs* : FORTEO; PARATHAR
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
parathyroid hormone (1-34), Leu(8),Asp(10),Lys(11),Ala(16),Gln(18),Thr(33),Ala(34)  0   *Peptide Fragments Teriparatide/*analogs & derivatives Parathyroid Hormone. Bone 1999 Nov;25(5):561-9
RS 66271  0   Teriparatide/*analogs & derivatives. J Bone Miner Res 1996 Dec;11(12):1943-51
parathyroid hormone (1-34), Arg(2)  136250-66-3   *Peptide Fragments Teriparatide/*analogs & derivatives. Endocrinology 1994 Sep;135(3):1186-94
parathyroid hormone (1-34), Ala(25,26,27)  0   *Peptide Fragments Teriparatide/*analogs & derivatives. J Pharmacol Exp Ther 1994 Jan;268(1):19-24
parathyroid hormone (1-34)amide, Nle(8), Nle(18), Tyr(34)  97930-52-4   *Peptide Fragments Teriparatide/*analogs & derivatives. Endocrinology 1989;125(5):2594
parathyroid hormone-related protein (1-34)  112540-82-6   *Peptide Fragments *Parathyroid Hormone-Related Protein Neoplasm Proteins Teriparatide.
Pharma Action Antihypertensive Agents 		Biochem Biophys Res Commun 1987;149(1):227
parathyroid hormone (1-34)amide  0   *Peptide Fragments Teriparatide/*analogs & derivatives. Chem Pharm Bull (Tokyo) 1982;30(5):1738

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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