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HIV Integrase Inhibitors

More information in Books or onNLM PubMed
Definition: Inhibitors of HIV INTEGRASE, an enzyme required for integration of viral DNA into cellular DNA.  DF: HIV INTEGRASE INHIB    Other names Inhibitors, HIV Integrase; Integrase Inhibitors, HIV
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
methyl 3-(2-(3-chloro-4-fluorobenzyl)-7-hydroxy-5-isopropyl-1,3,6-trioxo-2,3,5,6-tetrahydro-1H-pyrrolo(3,4-c)pyridin-4-yl)propanoate  0   *Imides *Pyridones HIV Integrase Inhibitors. Chem Biol Drug Des. 2012 Feb;79(2):157-65.
3-(4-fluoro-2-methoxy-benzyl)-7-hydroxy-8,9-dihydro-3H,7H-pyrrolo(2,3-c)(1,7)naphthyridin-6-one  0   *Naphthyridines HIV Integrase Inhibitors. Xenobiotica. 2012 Jan;42(1):57-74.
dolutegravir  0   *Heterocyclic Compounds, 3-Ring HIV Integrase Inhibitors. Antimicrob Agents Chemother 2010 Jan;54(1):254-8
integrastatin B  324518-09-4   *Heterocyclic Compounds, 3-Ring HIV Integrase Inhibitors. Org Biomol Chem. 2011 Aug 7;9(15):5354-7
integrastatin A  0   *Heterocyclic Compounds, 3-Ring HIV Integrase Inhibitors. Org Biomol Chem. 2011 Aug 7;9(15):5354-7
lamellarin alpha 20-sulfate  0   *Coumarins *Heterocyclic Compounds with 4 or More Rings *Isoquinolines HIV Integrase Inhibitors. J Med Chem 1999 Jun 3;42(11):1901-7

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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