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Vaccines, DNA

More information in Books or onNLM PubMed
Definition: Recombinant DNA vectors encoding antigens administered for the prevention or treatment of disease. The host cells take up the DNA, express the antigen, and present it to the immune system in a manner similar to that which would occur during natural infection. This induces humoral and cellular immune responses against the encoded antigens. The vector is called naked DNA because there is no need for complex formulations or delivery agents; the plasmid is injected in saline or other buffers.  vaccines composed of recombinant DNA vectors encoding antigens    Other names Vaccines, Polynucleotide; Vaccines, Nucleic Acid; Vaccines, Naked DNA; DNA Vaccines, Recombinant; DNA Vaccines, Naked; Vaccines, Recombinant DNA; Recombinant DNA Vaccines; Polynucleotide Vaccines; Nucleic Acid Vaccines; Naked DNA Vaccines; DNA Vaccines
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
SBm7462 vaccine  0   *Vaccines, DNA Vaccines, Subunit. Vet Immunol Immunopathol 2002 Sep 25;88(3-4):163-72
VCL-AB01 vaccine  0   *Vaccines, DNA *Anthrax Vaccines. Hum Vaccin 2009 Aug;5(8):536-44
VCL-CB01 vaccine  0   *Vaccines, DNA. Mol Biotechnol 2008 Sep;40(1):47-57
BHT 3009  0   *Vaccines, DNA. Curr Opin Mol Ther 2009 Aug;11(4):463-70
amolimogene bepiplasmid  0   *Vaccines, DNA *Cancer Vaccines. Curr Opin Mol Ther 2008 Dec;10(6):622-8
pGJA-P VAX vaccine  0   *Vaccines, DNA. J Gene Med 2008 Mar;10(3):298-305
pMBD2-mFlk-1 vaccine  0   *Vaccines, DNA. Clin Cancer Res 2007 Nov 15;13(22 Pt 1):6779-87
pTHr.HIVA  0   *AIDS Vaccines *Vaccines, DNA. AIDS 2005 Aug 12;19(12):1321-3
PfCSP DNA vaccine  0   *Malaria Vaccines *Vaccines, DNA Vaccines, Synthetic. Vaccine 2004 Apr 16;22(13-14):1592-603
heberbiovac-HB  0   *Vaccines, DNA Hepatitis B Vaccines. Rev Cubana Med Trop 1995;47(1):65-70

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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