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Bone Morphogenetic Proteins

More information in Books or onNLM PubMed
Definition: Bone-growth regulatory factors that are members of the transforming growth factor-beta superfamily of proteins. They are synthesized as large precursor molecules which are cleaved by proteolytic enzymes. The active form can consist of a dimer of two identical proteins or a heterodimer of two related bone morphogenetic proteins.  general; prefer specifics   
Examples Bone Morphogenetic Protein 1; Bone Morphogenetic Protein 2; Bone Morphogenetic Protein 3; Bone Morphogenetic Protein 4; Bone Morphogenetic Protein 5; Bone Morphogenetic Protein 6; Bone Morphogenetic Protein 7; Bone Morphogenetic Protein 15; Growth Differentiation Factor 2; Growth Differentiation Factor 10 		Other names Morphogenetic Proteins, Bone; Morphogenetic Protein, Bone; Bone Morphogenetic Protein
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
gremlin 2 protein, zebrafish  0   *Zebrafish Proteins *Intercellular Signaling Peptides and Proteins Bone Morphogenetic Proteins/antagonists & inhibitors. Development. 2011 Dec;138(23):5147-56
BMP10 protein, human  0   *Bone Morphogenetic Proteins. J Urol 2009 Jun;181(6):2749-59
BMP7b protein, zebrafish  0   *Bone Morphogenetic Proteins *Zebrafish Proteins. Gene Expr Patterns 2008 Jul;8(6):369-75
COLLOSS E  0   *Collagen *Bone Morphogenetic Proteins. Adv Exp Med Biol 2006;585:87-100
osteogenic protein 1 putty, recombinant human  0   *Bone Morphogenetic Proteins. J Bone Joint Surg Br. 2006 Jul;88(7):960-6
TG-pl-BMP-2 protein, recombinant  0   *Recombinant Fusion Proteins *Bone Morphogenetic Proteins. Biotechnol Bioeng 2005 Feb 5;89(3):253-62
admp protein, Xenopus  0   *Bone Morphogenetic Proteins *Xenopus Proteins.
Gdf7 protein, rat  0   *Bone Morphogenetic Proteins *Growth Differentiation Factors.
Gdf7 protein, mouse  0   *Bone Morphogenetic Proteins *Growth Differentiation Factors Transforming Growth Factor beta.
GDF7 protein, human  0   *Bone Morphogenetic Proteins *Growth Differentiation Factors.
cartilage-derived morphogenetic protein-3 protein, mouse  0   *Bone Morphogenetic Proteins Transforming Growth Factor beta. J Cell Physiol. 2004 Dec;201(3):401-8
GDF11 protein, human  0   *Bone Morphogenetic Proteins *Growth Differentiation Factors.
Ne-Osteo  0   *Bone Morphogenetic Proteins. Spine 2004 Mar 1;29(5);504-14
Sost protein, rat  0   *Genetic Markers *Bone Morphogenetic Proteins.
Sost protein, mouse  0   *Glycoproteins Bone Morphogenetic Proteins/antagonists & inhibitors.
BMP8A protein, human  0   *Bone Morphogenetic Proteins.
Bmp8a protein, mouse  0   *Bone Morphogenetic Proteins.
Sostdc1 protein, mouse  0   *Bone Morphogenetic Proteins. Biochem Biophys Res Commun 2004 Apr 2;316(2):490-500
SOSTDC1 protein, human  0   *Proteins Bone Morphogenetic Proteins/antagonists & inhibitors. Dev Biol 2003 Dec 1;264(1):91-105
BMPER protein, human  0   *Carrier Proteins Bone Morphogenetic Proteins. Mol Cell Biol. 2003 Aug;23(16):5664-79
SOST protein, human  0   *Genetic Markers *Bone Morphogenetic Proteins. Am J Hum Genet 2001 Mar;68(3):577-89
Bmp8b protein, mouse  0   *Bone Morphogenetic Proteins. Mech Dev 1996 Jul;57(21):1053-63
admp protein, zebrafish  0   *Bone Morphogenetic Proteins *Zebrafish Proteins. Mech Dev 2000 Feb;90(2):195-203
BMP8B protein, human  0   *Bone Morphogenetic Proteins. Blood Cells Mol Dis 1999 Oct-Dec;25(5-6):310-23
Tll2 protein, mouse  EC 3.4.24.-   *Tolloid-Like Metalloproteinases Bone Morphogenetic Proteins. Dev Biol 1999 Sep 15;213(2):283-300
BMP2/4 protein, Tripneustes gratilla  0   *Bone Morphogenetic Proteins. Biochem Biophys Res Commun 1999 May 10;258(2):457-63
Gdf11 protein, mouse  0   *Bone Morphogenetic Proteins *Growth Differentiation Factors. Mech Dev 1999 Feb;80(2):185-9
Bmp10 protein, mouse  0   *Bone Morphogenetic Proteins. Mech Dev 1999 Feb;80(2):181-4
BMP-11 protein, Xenopus  0   *Bone Morphogenetic Proteins *Xenopus Proteins. Dev Biol 1999 Apr 1;208(1):222-32
Cktsf1b1 protein, rat  0   *Bone Morphogenetic Proteins Apoptosis. Mol Cell Biol 1997 Aug;17(8):4801-10
cartilage-derived-morphogenetic protein-2  0   *Bone Morphogenetic Proteins Transforming Growth Factor beta. J Biol Chem 1994 Nov 11;269(45):28227-34
growth differentiation factor 7  0   *Bone Morphogenetic Proteins Transforming Growth Factor beta. Nature 1994 Apr 14;368(6472):639-43
noggin protein  148294-77-3   *Carrier Proteins Bone Morphogenetic Proteins/antagonists & inhibitors Xenopus Proteins Cystine Knot Motifs. Cell 1992 Sep 4;70(5):829-40

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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