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Protein Disulfide-Isomerases

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Definition: Sulfur-sulfur bond isomerases that catalyze the rearrangement of disulfide bonds within proteins during folding. Specific protein disulfide-isomerase isoenzymes also occur as subunits of PROCOLLAGEN-PROLINE DIOXYGENASE.     
See Also Procollagen-Proline Dioxygenase 		Other names Trypanothione Glutathione Thioltransferase; Transhydrogenase, Thiol-Disulfide; Thioltransferase, Trypanothione-Glutathione; Thiol Disulfide Transhydrogenase; Sulfhydryl Disulfide Interchange Enzyme; Site-Binding Protein, Glycosylation; Protein, Glycosylation Site-Binding; Protein Disulfide Isomerases; Isomerase, Protein Disulfide; Isomerase, Disulfide; Interchange Enzyme, Sulfhydryl-Disulfide; Interchange Enzyme, Disulfide; Glycosylation Site Binding Protein; Enzyme, Sulfhydryl-Disulfide Interchange; Enzyme, Disulfide Interchange; Disulfide-Isomerases, Protein; Disulfide-Isomerase, Protein; Disulfide Isomerase, Protein; Trypanothione-Glutathione Thioltransferase; Thiol-Disulfide Transhydrogenase
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
juniferdin  0   *Parabens *Sesquiterpenes Protein Disulfide-Isomerases/antagonists & inhibitors. ACS Chem Biol 2011 Mar 18;6(3):
Erp90 protein, human  EC 5.3.4.1   *Glycoproteins *Protein Disulfide-Isomerases. PLoS One 2011;6(2):e17037
dsbC protein, E coli  EC 5.3.4.1   *Protein Disulfide-Isomerases *Escherichia coli Proteins.
dsbA protein, E coli  EC 5.3.4.1   *Protein Disulfide-Isomerases *Escherichia coli Proteins.
Pdia5 protein, mouse  EC 5.3.4.1   *Protein Disulfide-Isomerases.
Pdia4 protein, mouse  EC 5.3.4.1   *Protein Disulfide-Isomerases.
Pdia2 protein, mouse  EC 5.3.4.1   *Protein Disulfide-Isomerases.
Pdia6 protein, mouse  EC 5.3.4.1   *Protein Disulfide-Isomerases.
PDIA5 protein, human  EC 5.3.4.1   *Protein Disulfide-Isomerases.
PDIA4 protein, human  EC 5.3.4.1   *Protein Disulfide-Isomerases.
PDIA2 protein, human  EC 5.3.4.1   *Protein Disulfide-Isomerases.
P4hb protein, rat  EC 5.3.4.1   *Procollagen-Proline Dioxygenase *Protein Disulfide-Isomerases.
P4hb protein, mouse  EC 5.3.4.1   *Procollagen-Proline Dioxygenase *Protein Disulfide-Isomerases.
P4HB protein, human  EC 5.3.4.1   *Procollagen-Proline Dioxygenase *Protein Disulfide-Isomerases.
Grp58 protein, rat  EC 5.3.4.1   *Protein Disulfide-Isomerases.
Pdia3 protein, mouse  EC 5.3.4.1   *Protein Disulfide-Isomerases.
PDI-2 protein, Trypanosoma brucei  EC 5.3.4.1   *Protozoan Proteins *Protein Disulfide-Isomerases. J Biol Chem 2005 Mar 18;280(11):10410-8
PDI-1 protein, Trypanosoma brucei  EC 5.3.4.1   *Protozoan Proteins *Protein Disulfide-Isomerases. J Biol Chem 2005 Mar 18;280(11):10410-8
TMX3 protein, human  EC 5.3.4.1   *Protein Disulfide-Isomerases. J Biol Chem 2005 Mar 4;280(9):8371-80
PDIA6 protein, human  EC 5.3.4.1   *Protein Disulfide-Isomerases. Blood. 2005 Feb 15;105(4):1500-7
DsbC-NL4-10K fusion protein  0   *Recombinant Fusion Proteins Protein Disulfide-Isomerases. Biomaterials 2005 Feb;26(6):679-86
Pdilt protein, mouse  EC 5.3.4.1   *Protein Disulfide-Isomerases. J Biol Chem 2005 Jan 14;280(2):1376-83
PDILT protein, human  EC 5.3.4.1   *Protein Disulfide-Isomerases. J Biol Chem 2005 Jan 14;280(2):1376-83
TXNDC5 protein, human  EC 5.3.4.1   *Protein Disulfide-Isomerases. J Biol Chem 2003 Nov 21;278(47):47079-88
protein disulfide isomerase-3, C elegans  EC 5.3.4.1   *Protein Disulfide-Isomerases *Caenorhabditis elegans Proteins. J Biol Chem 2003 Feb 7;278(6):4227-37
Eps1 protein, S cerevisiae  0   *Membrane Proteins *Molecular Chaperones *Saccharomyces cerevisiae Proteins Protein Disulfide-Isomerases. EMBO J 1999 Nov 1;18(21):5972-82
ERp38 protein, Neurospora crassa  EC 5.3.4.1   *Fungal Proteins *Heat-Shock Proteins *Protein Disulfide-Isomerases. Gene 1997 Jul 9;193(2):151-6
MPD1 protein, S cerevisiae  170350-44-4   *Repressor Proteins *Protein Disulfide-Isomerases *Saccharomyces cerevisiae Proteins. FEBS Lett 1995 Aug 7;369(2-3):212-6
PDIA3 protein, human  EC 5.3.4.1.   *Protein Disulfide-Isomerases Endoplasmic Reticulum Glutathione Molecular Chaperones. Arch Biochem Biophys 1994 Feb 1;308(2):454-60
PDI1 protein, S cerevisiae  0   *Protein Disulfide-Isomerases *Saccharomyces cerevisiae Proteins. J Biol Chem 1993 Apr 15;268(11):7728-32
EUG1 protein, S cerevisiae  EC 5.3.4.1   *Protein Disulfide-Isomerases *Saccharomyces cerevisiae Proteins. Mol Cell Biol 1992 Oct;12(10):4601-11
cognin  0   *Membrane Proteins Cell Adhesion Molecules Protein Disulfide-Isomerases. Prog Clin Biol Res 1980;42:171

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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