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Cromakalim

More information in Books or onNLM PubMed
Definition: A potassium-channel opening vasodilator that has been investigated in the management of hypertension. It has also been tried in patients with asthma. (Martindale, The Extra Pharmacopoeia, 30th ed, p352)     
Pharmacological Action Antihypertensive Agents; Bronchodilator Agents; Parasympatholytics; Vasodilator Agents 		Other names BRL38227; BRL38226; BRL 38227; BRL 38226; Lemakalim; Cromakalim, (trans)-Isomer; Cromakalim, (3S-trans)-Isomer; Cromakalim, (3S-cis)-Isomer; Cromakalim, (3R-trans)-Isomer; Cromakalim, (3R-cis)-Isomer; BRL-38227; BRL-38226; BRL-34915; Levcromakalim
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
1-(4-(2-ethoxy-4-methyl-1H-pyrrol-1-yl)-3-hydroxy-2,2-dimethylchroman-6-yl)-3-phenylurea  0   *Phenylurea Compounds Cromakalim/*analogs & derivatives. Int J Oncol. 2011 Dec;39(6):1609-17.
EMD 57970  0   Cromakalim/*analogs & derivatives. J Biol Chem 1996 Apr 12;271(15):8796-9
EMD 60480  0   Cromakalim/*analogs & derivatives. J Biol Chem 1996 Apr 12;271(15):8796-9
S 872342  0   Cromakalim/*analogs & derivatives. Investig Urol (Berl) 1994;5:225-9
S 870121  0   Cromakalim/*analogs & derivatives. Investig Urol (Berl) 1994;5:225-9

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