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Ryanodine Receptor Calcium Release Channel

More information in Books or onNLM PubMed
Definition: A tetrameric calcium release channel in the SARCOPLASMIC RETICULUM membrane of SMOOTH MUSCLE CELLS, acting oppositely to SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES. It is important in skeletal and cardiac excitation-contraction coupling and studied by using RYANODINE. Abnormalities are implicated in CARDIAC ARRHYTHMIAS and MUSCULAR DISEASES.      Other names Receptors, Ryanodine; Receptor Complex, Calcium-Ryanodine; Receptor 3, Ryanodine; Receptor 2, Ryanodine; Receptor 1, Ryanodine; Complex, Calcium-Ryanodine Receptor; Calcium Ryanodine Receptor Complex; Ca Release Channel Ryanodine Receptor; Ryanodine Receptor; RyR3; RyR2; Receptor, Ryanodine; Ca Release Channel-Ryanodine Receptor; Ryanodine Receptors; Ryanodine Receptor 3; Ryanodine Receptor 2; Ryanodine Receptor 1; RyR1; Calcium-Ryanodine Receptor Complex
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
hadrucalcin protein, Hadrurus gertschi  0   *Scorpion Venoms Ryanodine Receptor Calcium Release Channel. Br J Pharmacol 2009 Jun;157(3):392-403
1,1'-diheptyl-4,4'-bipyridinium  0   *Viologens Ryanodine Receptor Calcium Release Channel. Br J Pharmacol 1994 Aug;112(4):1216-22
ryanodine receptor calcium release channel (2460-2495), Ser(2474)  0   *Peptide Fragments *Ryanodine Receptor Calcium Release Channel. Biochem Biophys Res Commun 2002 Mar 8;291(4):1102-8
ryanodine receptor calcium release channel (2460-2495), synthetic  0   *Peptide Fragments *Ryanodine Receptor Calcium Release Channel. Biochem Biophys Res Commun 2002 Mar 8;291(4):1102-8
Unc-68 protein, C elegans  0   *Ryanodine Receptor Calcium Release Channel *Caenorhabditis elegans Proteins. J Cell Biol 1996 Aug;134(4):885-93
NF 307  0   *Naphthalenesulfonates *Oligopeptides Ryanodine Receptor Calcium Release Channel/agonists. Mol Pharmacol 1999 Mar;55(3):462-72

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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