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Hydroxymethyl and Formyl Transferases
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Definition
: Enzymes that catalyze the transfer of hydroxymethyl or formyl groups. EC 2.1.2.
Examples
Aminomethyltransferase
;
Glutamate Formimidoyltransferase
;
Glycine Hydroxymethyltransferase
;
Phosphoribosylaminoimidazolecarboxamide Formyltransferase
;
Phosphoribosylglycinamide Formyltransferase
Other names
Transferases, Hydroxymethyl; Transferases, Formyl; Transhydroxymethylases; Transformylases; Transformylase; Hydroxymethyltransferases; Hydroxymethyl Transferases; Formyltransferases; Formyl Transferases
Substance
CAS Registry & name
Categories
Source
Drugs
*
FONG protein, human
EC 2.1.2.-
*Hydroxymethyl and Formyl Transferases.
PLoS One 2011;6(5):e19641
Arakawa syndrome 1
0
*Metabolism, Inborn Errors
*Hyperhomocysteinemia
Hydroxymethyl and Formyl Transferases/deficiency.
DIT1 protein, S cerevisiae
EC 2.1.2.
*Hydroxymethyl and Formyl Transferases
*Saccharomyces cerevisiae Proteins.
Mol Cell Biol 2005 Aug;25(15):6772-88
purT protein, E coli
EC 2.1.2.-
*Hydroxymethyl and Formyl Transferases
*Escherichia coli Proteins.
inosine monophosphate synthase
0
*Multienzyme Complexes
*Nucleotide Deaminases
*Hydroxymethyl and Formyl Transferases.
Adv Exp Med Biol 1998;431:221-6
10-
formyl-
5,8-
10-
trideazafolic acid
143436-91-3
*Glutamates
*Quinazolines
Hydroxymethyl and Formyl Transferases/antagonists & inhibitors.
Bioorg Med Chem 1997 Sep;5(9):1817-30
deoxycytidylate hydroxymethyltransferase
EC 2.1.2.8
*Hydroxymethyl and Formyl Transferases.
formylmethanofuran-
tetrahydromethanopterin formyltransferase
EC 2.1.2.-
*Hydroxymethyl and Formyl Transferases.
J Biol Chem 1986;261(35):16653
dUMP-
hydroxymethylase
EC 2.1.2.-
*Hydroxymethyl and Formyl Transferases.
J Virol 13(4):828;1974
methionyl-
tRNA formyltransferase
EC 2.1.2.9
*Hydroxymethyl and Formyl Transferases.
Biochim Biophys Acta 477:356;1977
3-
methyl-
2-
oxobutanoate hydroxymethyltransferase
EC 2.1.2.11 5,10-
methylenetetrahydrofolate alpha-
ketoisovalerate hydroxymethyltransferase
*Hydroxymethyl and Formyl Transferases
Bacterial Proteins.
J Biol Chem 251(12):3780;1976; Methods Enzymol 62:204;1979
6-
hydroxymethylbenzo(alpha)pyrene synthetase
EC 2.1.2.-
*Hydroxymethyl and Formyl Transferases.
Arch Biochem Biophys 186(2):401;1978; Cancer Res 35(12):3731;1975; Carcinogenesis I W1 CA7624:p171;1976
deoxyhydroxymethylcytosine hydroxymethylase
EC 2.1.2.-
*Hydroxymethyl and Formyl Transferases.
Genetics 86(3):501;1977
benzopyrene hydroxymethylase
EC 2.1.2.-
*Hydroxymethyl and Formyl Transferases.
Arch Biochem Biophys 163(1):46;1974