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Alkyl and Aryl Transferases
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Definition
: A somewhat heterogeneous class of enzymes that catalyze the transfer of alkyl or related groups (excluding methyl groups). EC 2.5.
Examples
Cysteine Synthase
;
3-Deoxy-7-Phosphoheptulonate Synthase
;
Dihydropteroate Synthase
;
Dimethylallyltranstransferase
;
Farnesyl-Diphosphate Farnesyltransferase
;
Farnesyltranstransferase
;
Geranylgeranyl-Diphosphate Geranylgeranyltransferase
;
Geranyltranstransferase
;
Glutathione Transferase
;
Hydroxymethylbilane Synthase
;
Methionine Adenosyltransferase
;
3-Phosphoshikimate 1-Carboxyvinyltransferase
;
Riboflavin Synthase
;
Spermidine Synthase
;
Spermine Synthase
Other names
Aryltransferases; Alkyltransferases
Substance
CAS Registry & name
Categories
Source
Drugs
*
homogentisate geranylgeranyl transferase, Hordeum vulgare
EC 2.5.-
*Alkyl and Aryl Transferases.
Plant J. 2011 Jan;65(2):206-17.
coenzyme Q biosynthesis protein 2, Drosophila
EC 2.5.-
*Alkyl and Aryl Transferases
*Drosophila Proteins.
J Genet Genomics 2011 Jun 20;38(6):225-34
PPPS protein, Arabidopsis
EC 2.5.-
*Alkyl and Aryl Transferases
*Arabidopsis Proteins.
Plant Physiol 2011 Mar;155(3):1079-90
heme O synthase, Trypanosoma cruzi
EC 2.5.1.-
*Protozoan Proteins
*Alkyl and Aryl Transferases.
FEMS Microbiol Lett. 2010 Nov;312(2):133-41
prenyl diphosphate synthase, subunit 2, human
EC 2.5.1.-
*Alkyl and Aryl Transferases.
Anticancer Drugs 2009 Feb;20(2):141-8
quinolinate synthase, E coli
EC 2.5.-
*Alkyl and Aryl Transferases
*Escherichia coli Proteins.
FEBS Lett 2008 Aug 20;582(19):2937-44
DesVI protein, Streptomyces venezuelae
EC 2.5.1.-
*Alkyl and Aryl Transferases.
Biochemistry 2008 Apr 1;47(13):3982-8
homogentisate solanesyltransferase, Arabidopsis
EC 2.5.1.-
*Alkyl and Aryl Transferases
*Arabidopsis Proteins.
Planta 2007 Sep;226(4):1067-73
agmatine-
cadaverine aminopropyl transferase, Pyrococcus furiosus
EC 2.5.-
*Archaeal Proteins
*Alkyl and Aryl Transferases.
J Bacteriol 2007 Aug;189(16):6057-67
prenyldiphosphate synthase, subunit 1, human
EC 2.5.1.-
*Alkyl and Aryl Transferases.
J Clin Invest 2007 Mar;117(3):765-72
dammarenediol-
II synthase, Panax ginseng
EC 2.5.1.-
*Alkyl and Aryl Transferases.
FEBS Lett 2006 Oct 2;580(22):5143-9
COX10 protein, mouse
EC 2.5.1.-
*Membrane Proteins
*Alkyl and Aryl Transferases.
Mol Cell Biol. 2006 Jul;26(13):4872-81
Srt1 protein, S cerevisiae
EC 2.5.-
*Alkyl and Aryl Transferases
*Saccharomyces cerevisiae Proteins.
Mol Cell Biol 1999 Jan;19(1):471-83
germacrene A synthase, Artemisia annua
EC 2.5.1.-
*Alkyl and Aryl Transferases.
Arch Biochem Biophys 2006 Apr 15;448(1-2):3-12
ATL1 protein, S pombe
EC 2.5.-
*Alkyl and Aryl Transferases.
Nucleic Acids Res 2006;34(8):2347-54
thiamine phosphate synthase, Plasmodium falciparum
EC 2.5.-
*Alkyl and Aryl Transferases.
Biol Chem 2006 Jan;387(1):41-51
germacrene A synthase, Ixeris dentata
EC 2.5.1.-
*Alkyl and Aryl Transferases.
Biotechnol Lett 2005 Mar;27(5):285-8
alkyltransferase-
like protein, E coli
EC 2.5.1.-
*Alkyl and Aryl Transferases
*Escherichia coli Proteins
DNA Repair.
Nucleic Acids Res. 2005;33(12) (dup#5):3837-44
SPS2 protein, Arabidopsis
EC 2.5.1.11
*Alkyl and Aryl Transferases
*Arabidopsis Proteins.
Plant Cell Physiol 2004 Dec;45(12):1882-8
SPS1 protein, Arabidopsis
EC 2.5.1.11
*Alkyl and Aryl Transferases
*Arabidopsis Proteins.
Plant Cell Physiol 2004 Dec;45(12):1882-8
1,4-
dihydroxy-
2-
naphthoic acid phytyltransferase, Arabidopsis
EC 2.5.-
*Alkyl and Aryl Transferases
*Arabidopsis Proteins.
Plant J 2005 Feb;41(4):627-37
Rv2361c protein, Mycobacterium tuberculosis
EC 2.5.1.-
*Bacterial Proteins
*Alkyl and Aryl Transferases.
syn-
pimara-
7,15-
diene synthase, Oryza sativa
EC 2.5.1.-
*Plant Proteins
*Alkyl and Aryl Transferases.
Plant Physiol 2004 Aug;135(4):2098-105
COX10 protein, human
EC 1.9.3.1
*Electron Transport Complex IV
*Membrane Proteins
*Alkyl and Aryl Transferases.
CyoE protein, E coli
EC 2.5.1.-
*Alkyl and Aryl Transferases
*Escherichia coli Proteins.
BET2 protein, S cerevisiae
EC 2.5.1.-
*Alkyl and Aryl Transferases
*Saccharomyces cerevisiae Proteins.
BET4 protein, S cerevisiae
EC 2.5.1.60
*Alkyl and Aryl Transferases
*Saccharomyces cerevisiae Proteins.
Geranylgeranyltransferase type II
EC 2.5.1.-
*Alkyl and Aryl Transferases.
ptb1 protein, S pombe
0
*Alkyl and Aryl Transferases
*Schizosaccharomyces pombe Proteins
Protein Prenylation.
isopentenyl-
dimethylallyl diphosphate synthase, Nicotiana benthamiana
EC 2.5.1.-
*Alkyl and Aryl Transferases.
Plant Physiol 2004 Apr;134(4):1401-13
(E)-
4-
hydroxy-
3-
methylbut-
2-
enyl diphosphate synthase, Nicotiana benthamiana
EC 2.5.1.-
*Alkyl and Aryl Transferases.
Plant Physiol 2004 Apr;134(4):1401-13
valencene synthase, Citrus
EC 2.5.1.-
*Plant Proteins
*Alkyl and Aryl Transferases.
Plant J 2003 Dec;36(5):664-74
SLY1 protein, Arabidopsis
EC 2.5.1.29
*Alkyl and Aryl Transferases
*Arabidopsis Proteins.
Plant Cell 2003 May;15(5):1120-30
(+)-
3-
carene synthase, Picea abies
EC 2.5.1.-
*Alkyl and Aryl Transferases.
Plant Mol Biol 2003 Jan;51(1):119-33
germacrene D synthase
EC 2.5.1.-
*Alkyl and Aryl Transferases
Sesquiterpenes, Germacrane.
Plant Cell 2002 Oct;14(10):2325-38
germacrene A synthase, Cichorium intybus
EC 2.5.1.-
*Plant Proteins
*Alkyl and Aryl Transferases
Sesquiterpenes, Germacrane.
Plant Physiol 2002 May;129(1):134-44
geranyl diphosphate 4-
hydroxybenzoate geranyltransferase
EC 2.5.1.-
*Alkyl and Aryl Transferases.
J Biol Chem 2002 Feb 22;277(8):6240-6
HPT1 protein, Arabidopsis
EC 2.5.-
*Alkyl and Aryl Transferases
*Arabidopsis Proteins.
Plant Physiol 2001 Nov;127(3):1113-24
thiamin phosphate synthase
EC 2.5.-
*Alkyl and Aryl Transferases.
Biochemistry 2001 Aug 28;40(34):10095-102
levopimaradiene synthase
EC 2.5.1.-
*Alkyl and Aryl Transferases.
Arch Biochem Biophys 2001 Aug 15;392(2):263-9
aphidicolan-
16beta-
ol synthase
EC 2.5.1.-
*Alkyl and Aryl Transferases.
J Am Chem Soc 2001 May 30;123(21):5154-5
dimethylallyl diphosphate naringenin 8-
dimethylallyltransferase
EC 2.5.1.-
*Alkyl and Aryl Transferases.
Phytochemistry 2000 Aug;54(7):649-55
CarRP protein, Mucor circinelloides
0
*Fungal Proteins
*Multienzyme Complexes
*Intramolecular Lyases
*Alkyl and Aryl Transferases.
Eur J Biochem 2000 Sep;267(17):5509-19
phytyltransferase
EC 2.5.-
*Alkyl and Aryl Transferases.
J Biol Chem 2000 Mar 24;275(12):8523-30
Rv1086 protein, Mycobacterium tuberculosis
EC 2.5.1.-
*Bacterial Proteins
*Alkyl and Aryl Transferases.
J Biol Chem 2000 Jul 28;275(30):22876-81
amorpha-
4,11-
diene synthase
EC 2.5.1.-
*Alkyl and Aryl Transferases.
Phytochemistry 1999 Nov;52(5):843-54
BIM 46050
0
*Amino Acids, Cyclic
Alkyl and Aryl Transferases/antagonists & inhibitors.
Int J Cancer 1999 Oct 8;83(2):283-7
BIM 46068
0
*Amino Acids, Cyclic
Alkyl and Aryl Transferases/antagonists & inhibitors.
Int J Cancer 1999 Oct 8;83(2):283-7
estrone oxime 3-
O-
sulfamate
0
*Oximes
Estrone
Alkyl and Aryl Transferases.
J Med Chem 1999 Aug 12;42(16):3188-92
nicotianamine synthase
EC 2.5.-
*Alkyl and Aryl Transferases.
Plant Physiol 1999 Feb;119(2):471-9
S-
(1,2-
dicarboxyethyl)glutathione synthetase
EC 2.5.1.-
*Alkyl and Aryl Transferases.
Biol Pharm Bull 1999 Jan;22(1):21-5
CPS protein, Gibberella fujikuroi
EC 2.5.1.-
*Fungal Proteins
*Alkyl and Aryl Transferases
Terpenes.
Curr Genet 1998 Sep;34(3):234-40
BTH1 protein, Brassica napus
EC 2.-
*Multienzyme Complexes
*Plant Proteins
*Phosphotransferases (Phosphate Group Acceptor)
*Alkyl and Aryl Transferases.
Plant Mol Biol 1998 Aug;37(6):955-66
(E)-
alpha-
bisabolene synthase
EC 2.5.1.-
*Alkyl and Aryl Transferases
Sesquiterpenes.
Proc Natl Acad Sci U S A 1998 Jun 9;95(12):6756-61
geranylpyrophosphate olivetolate geranyltransferase
EC 2.5.1.-
*Alkyl and Aryl Transferases.
FEBS Lett 1998 May 8;427(2):283-5
MenA protein, E coli
EC 2.5.1.-
*Alkyl and Aryl Transferases
*Escherichia coli Proteins.
J Bacteriol 1998 May;180(10):2782-7
germacrene C synthase
EC 2.5.1.-
*Alkyl and Aryl Transferases
Sesquiterpenes, Germacrane.
Proc Natl Acad Sci U S A 1998 Mar 3;9595):2216-21
delta-
selinene synthase
EC 2.5.1.-
*Alkyl and Aryl Transferases
Sesquiterpenes.
J Biol Chem 1998 Jan 23;273(4):2078-89
gamma-
humulene synthase
EC 2.5.1.-
*Alkyl and Aryl Transferases
Sesquiterpenes.
J Biol Chem 1998 Jan 23;273(4):2078-89
terpene synthase
EC 2.5.1.-
*Alkyl and Aryl Transferases
Arabidopsis Proteins.
Gene 1997 Oct 15;199(1-2):241-53
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