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Activated Protein C Resistance

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Definition: A hemostatic disorder characterized by a poor anticoagulant response to activated protein C (APC). The activated form of Factor V (Factor Va) is more slowly degraded by activated protein C. Factor V Leiden mutation (R506Q) is the most common cause of APC resistance.     
See Also Protein C Deficiency 		Other names Resistance, APC; APC Resistance
 
SubstanceCAS Registry & nameCategoriesSource
factor V Leiden  0   *Factor V Point Mutation Activated Protein C Resistance. Blood Coagul Fibrinolysis 1995 May;6(3):286-7

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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