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Natriuretic Peptide, C-Type

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Definition: A PEPTIDE of 22 amino acids, derived mainly from cells of VASCULAR ENDOTHELIUM. It is also found in the BRAIN, major endocrine glands, and other tissues. It shares structural homology with ATRIAL NATRIURETIC FACTOR. It has vasorelaxant activity thus is important in the regulation of vascular tone and blood flow. Several high molecular weight forms containing the 22 amino acids have been identified.     
Pharmacological Action Natriuretic Agents 		Other names Peptide-53, C-Type Natriuretic; Peptide-22, C-Type Natriuretic; Peptide, C-Type Natriuretic; Natriuretic Peptide-53, C-Type; Natriuretic Peptide-22, C-Type; Natriuretic Peptide, C Type; C Type Natriuretic Peptide 53; C Type Natriuretic Peptide 22; C Type Natriuretic Peptide; CNP-53; CNP-22; C-Type Natriuretic Peptide-53; C-Type Natriuretic Peptide-22; C-Type Natriuretic Peptide
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
natriuretic peptide precursor type C, mouse  0   *Protein Precursors *Natriuretic Peptide, C-Type. Science. 2010 Oct 15;330(6002):366-9
CD-NP natriuretic peptide  0   *Elapid Venoms *Natriuretic Peptide, C-Type. J Clin Pharmacol. 2009 Jun;49(6):668-73
amino-terminal pro-C-type natriuretic peptide, human  0   *Natriuretic Peptide, C-Type. Hypertension 2004 Jan;43(1):94-100
CIOR protein, mouse  0   *Natriuretic Peptide, C-Type. Calcif Tissue Int 2002 Feb;70(2):111-6
Nppa protein, mouse  0   *Protein Precursors *Natriuretic Peptide, C-Type. Nat Genet 2001 Jul;28(3):276-80

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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