Definition: An in situ method for detecting areas of DNA which are nicked during APOPTOSIS. Terminal deoxynucleotidyl transferase is used to add labeled dUTP, in a template-independent manner, to the 3 prime OH ends of either single- or double-stranded DNA. The terminal deoxynucleotidyl transferase nick end labeling, or TUNEL, assay labels apoptosis on a single-cell level, making it more sensitive than agarose gel electrophoresis for analysis of DNA FRAGMENTATION.
Other names Nick End Labelling, In Situ; Nick End Labeling, In Situ; Nick-End Labelling, In Situ; Nick End-Labelling, In Situ; Nick End-Labeling, In Situ; In Situ Nick-End Labelling; In Situ Nick End-Labelling; In Situ Nick End-Labeling; In Situ Nick End Labelling; In Situ Nick End Labeling; TUNEL; Nick-End Labeling, In Situ
