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Poloxamer

More information in Books or onNLM PubMed
Definition: A nonionic polyoxyethylene-polyoxypropylene block co-polymer with the general formula HO(C2H4O)a(-C3H6O)b(C2H4O)aH. It is available in different grades which vary from liquids to solids. It is used as an emulsifying agent, solubilizing agent, surfactant, and wetting agent for antibiotics. Poloxamer is also used in ointment and suppository bases and as a tablet binder or coater. (Martindale The Extra Pharmacopoeia, 31st ed)     
Pharmacological Action Excipients; Surface-Active Agents 		Other names Pluronic L81; Pluronic L121; Pluronic L101; Pluronic L 81; Pluronic L 121; Pluronic L 101; Pluronic F127; Pluronic F108; Pluronic F 68; Pluronic F 127; Pluronic F 108; Poloxamer 407; Poloxamer 338; Poloxamer 2930; Poloxamer 213; Poloxamer 188; Poloxalkol; Pluronics; Pluronic L-81; Pluronic L-121
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Lumagel  0   *Iohexol *Poloxamer Contrast Media. Urology. 2011 Dec;78(6):1435-41
Orthoblast II  0   *Poloxamer. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2010 Jun;109(6):e6-11
LeGoo  0   *Poloxamer. J Reconstr Microsurg 2009 Jan;25(1):69-76
pre-seed  0   *Poloxamer Cellulose/*analogs & derivatives. Fertil Steril 2008 Feb;89(2):375-9
pluronic P105  0   *Poloxamer. Technol Cancer Res Treat 2007 Feb;6(1):49-56
pluronic L64  0   *Poloxamer. J Colloid Interface Sci 2005 Jun 1;286(1):369-77
Ostene  0   *Poloxamer. J Craniofac Surg 2006 May;17(3):420-5; Neurosurgery 2001 Oct;49(4):962-7
SP1017  0   *Poloxamer. J Gene Med 2004 Jan;6(1):111-8
SP 1049C  0   Doxorubicin/*analogs & derivatives Poloxamer/*analogs & derivatives. Br J Cancer 2004 Jun 1;90(11):2085-91
pluronic L61  0   *Poloxamer. Chemistry. 2003 Aug 18;9(16):3930-6
pseudopolyrotaxane  0   *Cyclodextrins *Poloxamer *Rotaxanes. Spectrochim Acta A Mol Biomol Spectrosc 2003 Jan 15;59(2):285-9
polyrotaxane  0   *Cyclodextrins *Poloxamer *Rotaxanes. Spectrochim Acta A Mol Biomol Spectrosc 2003 Jan 15;59(2):285-9
poloxamer-iodone  26617-87-8   *Iodine *Poloxamer Drug Combinations. Mod Vet Pract 59(12):914;1978

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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