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GTPase-Activating Proteins

More information in Books or onNLM PubMed
Definition: Proteins that activate the GTPase of specific GTP-BINDING PROTEINS.     
Pharmacological Action GTP Phosphohydrolase Activators
Examples Chimerin Proteins; Eukaryotic Initiation Factor-5; ras GTPase-Activating Proteins; RGS Proteins
Other names GTPase Activating Proteins; GTPase Activating Protein; GTPase-Activating Protein; GAP Protein; GAP Proteins
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Tbc1d23 protein, mouse  0   *GTPase-Activating Proteins. J Immunol. 2012 Mar 15;188(6):2905-13
ACAP2 protein, mouse  0   *GTPase-Activating Proteins. J Cell Biol. 2000 Oct 30;151(3):627-38.
FAM13A protein, human  0   *GTPase-Activating Proteins. Biochem Biophys Res Commun. 2011 Nov 18;415(2):284-7
MgcRabGAP protein, mouse  0   *Microfilament Proteins *GTPase-Activating Proteins. Int J Androl. 2011 Oct;34(5 Pt 2):e358-67.
RhoGAP22 protein, human  0   *GTPase-Activating Proteins. Mol Cell Biol. 2011 Dec;31(23):4789-800.
CNT-2 protein, C elegans  0   *GTPase-Activating Proteins *Caenorhabditis elegans Proteins. Curr Biol 2011 Jun 7;21(11):948-54
Sh3bp1 protein, rat  0   *GTPase-Activating Proteins. Mol Cell 2011 Jun 10;42(5):650-61
ARHGAP30 protein, human  0   *GTPase-Activating Proteins. Biochem Biophys Res Commun. 2011 May 27;409(1):96-102
OATL1 protein, mouse  0   *GTPase-Activating Proteins. J Cell Biol 2011 Mar 7;192(5):839-53
TBC-2 protein, C elegans  0   *GTPase-Activating Proteins *Caenorhabditis elegans Proteins.
Age1 protein, S cerevisiae  0   *GTPase-Activating Proteins *Saccharomyces cerevisiae Proteins. J Biol Chem 2011 Feb 18;286(7):5187-96
TAGAP protein, human  0   *GTPase-Activating Proteins. Arthritis Res Ther 2010;12(5):R175
p190B RhoGAP, Xenopus  0   *GTPase-Activating Proteins *Xenopus Proteins. J Cell Sci 2010 Dec 1;123(Pt 23):4128-44
SRGP-1 protein, C elegans  0   *GTPase-Activating Proteins *Caenorhabditis elegans Proteins. Nat Cell Biol. 2011 Jan;13(1):79-86
Git2b protein, zebrafish  0   *GTPase-Activating Proteins *Zebrafish Proteins Cell Adhesion Molecules. Dev Biol 2011 Jan 15;349(2):225-37
Git2a protein, zebrafish  0   *GTPase-Activating Proteins *Zebrafish Proteins Cell Adhesion Molecules. Dev Biol 2011 Jan 15;349(2):225-37
TBC1D16 protein, human  0   *GTPase-Activating Proteins. Cell 2010 Dec 10;143(6):1005-17
SMAP1L protein, human  0   *Membrane Proteins *GTPase-Activating Proteins. J Asthma. 2010 Nov;47(9):959-65
Abr protein, rat  0   *GTPase-Activating Proteins. J Neurosci 2010 Oct 20;30(42):14134-44
AGAP1 protein, mouse  0   *GTPase-Activating Proteins. EMBO J. 2010 Aug 18;29(16):2813-26
Agap1 protein, rat  0   *GTPase-Activating Proteins. EMBO J. 2010 Aug 18;29(16):2813-26
Yih1 protein, E coli  0   *GTPase-Activating Proteins *Escherichia coli Proteins. J Mol Biol 2010 Jun 25;399(5):759-72
Rho GTPase activating protein 11A, Xenopus  0   *GTPase-Activating Proteins *Xenopus Proteins. Dev Biol. 2010 Aug 1;344(1):26-35
Git2 protein, Xenopus  0   *GTPase-Activating Proteins *Xenopus Proteins. Dev Biol. 2010 Aug 1;344(1):26-35
TBC1D15 protein, human  0   *GTPase-Activating Proteins. J Biol Chem 2010 May 28;285(22):16814-21
Git2 protein, rat  0   *GTPase-Activating Proteins. Biol Cell 2010;102(4):231-44
TBC1D2 protein, human  0   *GTPase-Activating Proteins. Curr Biol. 2010 Feb 9;20(3):198-208
Dsyd1 protein, Drosophila  0   *GTPase-Activating Proteins *Drosophila Proteins. J Cell Biol 2010 Feb 22;188(4):565-79
CHIN-1 protein, C elegans  0   *GTPase-Activating Proteins *Caenorhabditis elegans Proteins. Mol Biol Cell 2010 Jan;21(2):266-77
CCDC125 protein, mouse  0   *GTPase-Activating Proteins. Int J Mol Med. 2009 Nov;24(5):605-11
CCDC125 protein, human  0   *GTPase-Activating Proteins. Int J Mol Med. 2009 Nov;24(5):605-11
NEV protein, Arabidopsis  0   *GTPase-Activating Proteins *Arabidopsis Proteins. Development 2009 Jun;136(11):1909-18
Sipa1l1 protein, mouse  0   *GTPase-Activating Proteins. Neuroscience 2009 Aug 18;162(2):404-14
TBC1D5 protein, human  0   *GTPase-Activating Proteins. J Cell Sci. 2009 Jul 15;122(Pt 14); 2371-82
ARHGAP18 protein, human  0   *GTPase-Activating Proteins. Mol Psychiatry. 2009 Apr;14(4):416-28
CENTB5 protein, mouse  0   *GTPase-Activating Proteins *Membrane Transport Proteins. Mol Biol (Mosk). 2009 May-Jun;43(3):407-13
CENTB5 protein, human  0   *GTPase-Activating Proteins *Membrane Transport Proteins. Mol Biol (Mosk). 2009 May-Jun;43(3):407-13
MSB4 protein, S cerevisiae  0   *GTPase-Activating Proteins *Saccharomyces cerevisiae Proteins.
MSB3 protein, S cerevisiae  0   *GTPase-Activating Proteins *Saccharomyces cerevisiae Proteins.
Rich2 protein, human  0   *GTPase-Activating Proteins. J Cell Biol 2009 Mar 9;184(5):721-36
Rap1GAP protein, mouse  0   *GTPase-Activating Proteins. Proc Natl Acad Sci U S A 2009 Mar 3;106(9):3531-6
CG16728 protein, Drosophila  0   *GTPase-Activating Proteins *Drosophila Proteins. Dev Biol 2009 Jan 1;325(1):15-23
SIPA1L1 protein, human  0   *GTPase-Activating Proteins. J Biol Chem 2008 Oct 24;283(43):29424-32
Gap-3 protein, C elegans  0   *GTPase-Activating Proteins *Caenorhabditis elegans Proteins. Dev Biol 2008 Nov 15;323(2):166-76
MacGAP protein, human  0   *GTPase-Activating Proteins. Acta Biochim Biophys Sin (Shanghai). 2008 Oct;40(10):855-63
LOC686547 protein, rat  0   *GTPase-Activating Proteins. Am J Physiol Cell Physiol 2008 Oct;295(4):C1016-25
AGD1 protein, Arabidopsis  0   *GTPase-Activating Proteins *Arabidopsis Proteins. Plant Physiol 2008 Aug;147(4);1659-74
IQGAP3 protein, mouse  0   *GTPase-Activating Proteins. Nat Cell Biol 2008 Aug;10(8):971-8
SRGAP3 protein, rat  0   *GTPase-Activating Proteins. Cell Mol Neurobiol 2008 Feb;28(2):205-21
srGAP2 protein, rat  0   *GTPase-Activating Proteins. Cell Mol Neurobiol 2008 Feb;28(2):205-21
srGAP1 protein, rat  0   *GTPase-Activating Proteins. Cell Mol Neurobiol 2008 Feb;28(2):205-21
OPHN1 protein, rat  0   *Cytoskeletal Proteins *Nuclear Proteins *GTPase-Activating Proteins. Methods Enzymol 2008;439():255-66
Rga4 protein, S pombe  0   *GTPase-Activating Proteins *Schizosaccharomyces pombe Proteins. Curr Biol 2008 Mar 11;18(5):322-30
P-Rex2 protein, mouse  0   *GTPase-Activating Proteins. Proc Natl Acad Sci U S A 2008 Mar 18;105(11):4483-8
Spa-1 protein, human  0   *GTPase-Activating Proteins. Int J Dev Biol 2008;52(1):43-53
Rga1 protein, S cerevisiae  0   *GTPase-Activating Proteins *Saccharomyces cerevisiae Proteins. J Cell Biol 2007 Dec 31;179(7):1375-84
TBC1D1 protein, human  0   *GTPase-Activating Proteins. Biochem J 2008 Jan 15;409(2):449-59
TAT-RasGAP(317-326)  0   *Peptide Fragments *GTPase-Activating Proteins. Oncogene 2004 Nov 25;23(55):8971-8
RGA-4 protein, C elegans  0   *GTPase-Activating Proteins *Caenorhabditis elegans Proteins. Proc Natl Acad Sci U S A 2007 Sep 18;104(38):14976-81
RGA-3 protein, C elegans  0   *GTPase-Activating Proteins *Caenorhabditis elegans Proteins. Proc Natl Acad Sci U S A 2007 Sep 18;104(38):14976-81
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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