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Leptin

More information in Books or onNLM PubMed
Definition: A 16-kDa peptide hormone secreted from WHITE ADIPOCYTES. Leptin serves as a feedback signal from fat cells to the CENTRAL NERVOUS SYSTEM in regulation of food intake, energy balance, and fat storage.      Other names Gene Product, Obese; Gene Product, Ob; Obese Gene Product; Ob Gene Product; Obese Protein; Ob Protein
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Tat-leptin  0   *Leptin *tat Gene Products, Human Immunodeficiency Virus. Exp Clin Endocrinol Diabetes. 2010 Jan;118(1):31-7
murine leptin analog  0   *Recombinant Proteins Leptin/*analogs & derivatives. Endocrinology 2007 Jun;148(6):2878-85
leptin 57-92  0   *Peptide Fragments *Leptin. Clin Endocrinol (Oxf). 2004 Apr;60(4):434-41
leptin 22-56  0   *Peptide Fragments *Leptin. Clin Endocrinol (Oxf). 2004 Apr;60(4):434-41
pegylated leptin  0   *Polyethylene Glycols Leptin/*analogs & derivatives Recombinant Proteins. J Clin Endocrinol Metab 2004 Apr;89(4):1773-8
LY396623  0   Leptin/*analogs & derivatives. J Pharm Biomed Anal 2000 Sep;23(4):687-96
metreleptin  186018-45-1   Leptin/*analogs & derivatives. Clin Pharmacol Ther. 2000 Oct;68(4):455
leptin (116-130)  0   *Peptide Fragments *Leptin Leptin/agonists. Endocrinology 2000 Jul;141(7):2501-7
leptin(116-130) amide  0   *Peptide Fragments Leptin. Eur J Endocrinol 2000 Apr;142(4):406-10
recombinant methionyl human leptin  0   Leptin/*analogs & derivatives Obesity/drug therapy. JAMA 1999 Oct 27;282(16):1517-8

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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