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Matrix Metalloproteinase 8

More information in Books or onNLM PubMed
Definition: A member of the MATRIX METALLOPROTEINASES that cleaves triple-helical COLLAGEN types I, II, and III.      Other names MMP-8 Metalloproteinase; Metalloproteinase-8, Matrix; Metalloproteinase, MMP8; Metalloproteinase, MMP-8; Metalloproteinase 8, Matrix; MMP 8 Metalloproteinase; Collagenase, Neutrophil; Collagenase, Fibroblast; Collagenase 2; Matrix Metalloproteinase-8; MMP8 Metalloproteinase; Neutrophil Collagenase; Fibroblast Collagenase; Collagenase-2
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
(1-(4'-methoxybiphenyl-4-sulfonylamino)-2-methylpropyl) phosphonate  0   *Phosphonic Acids *Sulfonamides Matrix Metalloproteinase 8/antagonists & inhibitors. J Med Chem 2007 Jan 25;50(2):211-8
MMP8 protein, human  EC 3.4.24.-   *Matrix Metalloproteinase 8. Ann Rheum Dis 2004 Jul;63(7):881-3
prolyl-leucyl-tryptophanphosphonic acid  0   *Oligopeptides *Phosphonic Acids Matrix Metalloproteinase 8/antagonists & inhibitors. J Med Chem 2000 Sep 7;43(18):3377-85
2-(biphenyl-4-ylsulfonyl)-1,2,3,4-tetrahydroisoquinolin-3-carboxylic acid  0   *Sulfones *Tetrahydroisoquinolines Matrix Metalloproteinase 8/antagonists & inhibitors. J Med Chem 2000 Sep 7;43(18):3377-85
YLL 224  0   *Imines *Indoles Matrix Metalloproteinase 3/antagonists & inhibitors Matrix Metalloproteinase 2/antagonists & inhibitors Matrix Metalloproteinase 9/antagonists & inhibitors Matrix Metalloproteinase 1/antagonists & inhibitors Matrix Metalloproteinase 7/antagonists & inhibitors Matrix Metalloproteinase 8/antagonists & inhibitors. Biochem Biophys Res Commun 2000 Aug 11;274(3):780-6
MAG 283  0   *Amides *Sulfhydryl Compounds Matrix Metalloproteinase 3/antagonists & inhibitors Matrix Metalloproteinase 2/antagonists & inhibitors Matrix Metalloproteinase 9/antagonists & inhibitors Matrix Metalloproteinase 1/antagonists & inhibitors Matrix Metalloproteinase 7/antagonists & inhibitors Matrix Metalloproteinase 8/antagonists & inhibitors. Biochem Biophys Res Commun 2000 Aug 11;274(3):780-6

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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