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Receptor, trkB

More information in Books or onNLM PubMed
Definition: A protein-tyrosine kinase receptor that is specific for BRAIN-DERIVED NEUROTROPHIC FACTOR; NEUROTROPHIN 3; neurotrophin 4 and neurotrophin 5. It is widely expressed in nervous tissue and plays a role in mediating the effects of neurotrophins on growth and differentiation of neuronal cells.  DF: RECEPT TRKB    Other names trkB(gp145) Protein; Receptor, Neurotrophic Tyrosine Kinase Type 2; Neurotrophic Tyrosine Kinase Receptor Type 2; Brain Derived Neurotrophic Factor Receptor; Receptor, NTRK2; Receptor, BDNF; trkB Receptor; Neurotrophic Factor, Brain-Derived, Receptor; NTRK2 Receptor; BDNF Receptor
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
ANA 12 compound  0   *Azepines *Benzamides Receptor, trkB/antagonists & inhibitors. J Clin Invest 2011 May 2;121(5):1846-57

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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