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Tissue Kallikreins

More information in Books or onNLM PubMed
Definition: A family of trypsin-like SERINE ENDOPEPTIDASES that are expressed in a variety of cell types including human prostate epithelial cells. They are formed from tissue prokallikrein by action with TRYPSIN. They are highly similar to PROSTATE-SPECIFIC ANTIGEN. EC 3.4.21.35.  do not confuse PROSTATE SPECIFIC KALLIKREIN with PROSTATE SPECIFIC ANTIGEN    Other names Specific Kallikrein, Prostate; Kallikreins, Tissue; Kallikreins, Human Glandular; Kallikrein-1, Glandular; Kallikrein, hK2; Kallikrein, hK1; Kallikrein, Urinary; Kallikrein, Tissue; Kallikrein, Prostate Specific; Kallikrein, Pancreatic; Kallikrein, Glandular; Glandular Kallikreins, Human; Glandular Kallikrein 1; 2, Kallikrein; 1, Kallikrein; Tissue Kallikrein; Prostate Specific Kallikrein; Kallikrein 2; Kallikrein 1; Glandular Kallikrein-1
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
KLKP1 protein, human  0   *Tissue Kallikreins. Prostate 2006 Jun 15;66(9):936-44
Klk13 protein, mouse  EC 3.4.99.-   *Tissue Kallikreins.
blarina toxin, Blarina brevicauda  EC 3.4.21.35   *Tissue Kallikreins. Proc Natl Acad Sci U S A 2004 May 18;101(20):7542-7
mK1 protein, mouse  EC 3.4.21.-   *Tissue Kallikreins. J Cardiovasc Pharmacol 2003 Dec;42 Suppl 1S49-53
FE 999024  0   *Peptides Tissue Kallikreins/antagonists & inhibitors. Am J Pathol 2001 Nov;159(5):1797-805
phenylacetyl-Phe-Ser-Arg-N-(2,4-dinitrophenyl)ethylenediamine  0   *Oligopeptides Tissue Kallikreins/antagonists & inhibitors. Br J Pharmacol 2000 Jul;130(5):1099-107
tonin  EC 3.4.21.-   *Tissue Kallikreins.

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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