Estrogen Receptor Modulators (definition)

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ψ ψ	Estrogen Receptor Modulators

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Definition: Substances that possess antiestrogenic actions but can also produce estrogenic effects as well. They act as complete or partial agonist or as antagonist. They can be either steroidal or nonsteroidal in structure.

do not confuse with SELECTIVE ESTROGEN RECEPTOR MODULATORS
See Also Estrogen Antagonists; Estrogens
Examples Estrogen Antagonists; Selective Estrogen Receptor Modulators

Other names Receptor Modulators, Estrogen; Receptor Modulator, Estrogen; Modulators, Estrogen Receptor; Modulator, Estrogen Receptor; Estrogen Receptor Modulator; Antiestrogen; Antiestrogens

Substances having this pharmacologic action: tibolone

Substance	CAS Registry & name	Categories	Source	Drugs*
4-(2-phenyl-5,7-bis(trifluoromethyl)pyrazolo(1,5-a)pyrimidin-3-yl)phenol	0	Pyrazoles Pyrimidines Estrogen Receptor Modulators.	Horm Behav 2010 Nov;58(5):872-7
tremifene	0	Organic Chemicals Breast Neoplasms Estrogen Receptor Modulators.	Oncol Rep 2000 May-Jun;7(3):479-84
fulvestrant	129453-61-8	Estradiol/analogs & derivatives Estrogen Receptor Modulators. Pharma Action* Antineoplastic Agents ; Estrogen Antagonists ; Antineoplastic Agents, Hormonal	J Cancer Res 1991;51(15):3867	FASLODEX

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor

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