Calcium Channels (definition)

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Calcium Channels, N-Type

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Definition: CALCIUM CHANNELS that are concentrated in neural tissue. Omega toxins inhibit the actions of these channels by altering their voltage dependence.

DF: VDCC N
Examples Calcium Channels, P-Type; Calcium Channels, Q-Type; Calcium Channels, R-Type

Other names VDCC, N-Type; Neural Type Calcium Channels; N Type Voltage Dependent Calcium Channels; N Type VDCC; N Type Calcium Channels; N Type Calcium Channel; Channels, Neural-Type Calcium; Channels, N-Type Calcium; Channel, N-Type Calcium; Calcium Channels, Neural-Type; Calcium Channels, N Type; Calcium Channel, N-Type; N-Type Voltage-Dependent Calcium Channels; N-Type Calcium Channel; N-Type VDCC; Neural-Type Calcium Channels; N-Type Calcium Channels

Substance	CAS Registry & name	Categories	Source	Drugs*
1-(6,6-bis(4-fluorophenyl)hexyl)-4-(3,4,5-trimethoxybenzyl)piperazine	0	*Piperazines Calcium Channels, T-Type Calcium Channels, N-Type.	J Neurosci 2008 Nov 5;28(45):11712-9
CaV2.2 protein, Xenopus	0	Calcium Channels, N-Type Xenopus Proteins.	J Neurosci. 2008 Mar 5;28(10):2366-74
Cav2.2 protein, rat	0	*Calcium Channels, N-Type.	Neuron 2004 Jan 8;41(1):127-38
Cacna1b protein, mouse	0	*Calcium Channels, N-Type.	FEBS Lett 1994 Jan 24;338(1):1-5
CACNA1B protein, human	0	*Calcium Channels, N-Type.	Science 1992 Jul 17;257(5068):389-95
1-(4-aminopiperidin-1-yl)-4,4-bis(fluorophenyl)butan-1-one	0	Butanones Piperidines Calcium Channels, N-Type/antagonists & inhibitors.	J Med Chem 2004 Nov 18;47(24):6070-81
PD 181283	0	Aniline Compounds Leucine/analogs & derivatives Calcium Channels, N-Type/antagonists & inhibitors.	Bioorg Med Chem Lett 1999 Aug 16;9(16):2453-8
voltage-dependent calcium channel (P-Q type)	0	*Calcium Channels, N-Type.	Trends Neurosci 1995 Feb;18(2):89-98
ziconotide	107452-89-1	omega-Conotoxins Calcium Channels, N-Type. Pharma Action* Calcium Channel Blockers ; Neuroprotective Agents ; Analgesics, Non-Narcotic	J Cardiovasc Pharmacol 1992;20(5):756-64	PRIALT

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor

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