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Cyclophilins

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Definition: A family of peptidyl-prolyl cis-trans isomerases that bind to CYCLOSPORINS and regulate the IMMUNE SYSTEM. EC 5.2.1.-     
Examples Cyclophilin A 		Other names Proteins, Cyclosporin-Binding; Protein, Cyclosporin-Binding; Cyclosporin Binding Proteins; Cyclosporin Binding Protein; Cyclosporin-Binding Protein; Cyclosporin-Binding Proteins; Cyclophilin
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
SQN protein, Arabidopsis  EC 5.2.1.-   *Cyclophilins *Arabidopsis Proteins. J Biol Chem. 2011 Nov 4;286(44):38184-9.
2-(3-chloro-4-fluorophenyl)isothiazol-3-one  0   *Thiazoles Peptidylprolyl Isomerase/antagonists & inhibitors Cyclophilins/antagonists & inhibitors. Biochem Biophys Res Commun 2011 Mar 18;406(3):439-43
ROC4 protein, Arabidopsis  EC 5.2.1.-   *Cyclophilins *Arabidopsis Proteins. Photochem Photobiol 2008 Nov-Dec;84(6):1343-8
cyclophilin 71, Arabidopsis  EC 5.2.1.-   *Cyclophilins *Arabidopsis Proteins. Plant Cell 2007 Aug;19(8):2403-16
CYP20-2 protein, Arabidopsis  EC 5.2.1.-   *Cyclophilins *Arabidopsis Proteins. Plant Physiol 2004 Apr;134(4):1268-82
Rct1 protein, S pombe  0   *Cyclophilins *Schizosaccharomyces pombe Proteins. Mol Cell Biol 2007 May;27(10):3601-11
ROC1 protein, Arabidopsis  EC 5.2.1.-   *Cyclophilins *Arabidopsis Proteins. Mol Microbiol 2006 Sep;61(6):1485-96
cyclophilin 59, Arabidopsis  EC 5.2.1.-   *Cyclophilins *Arabidopsis Proteins. Plant Physiol 2004 Apr;134(4):1268-82
cyclophilin 38, Arabidopsis  EC 5.2.1.-   *Cyclophilins *Arabidopsis Proteins. Plant Physiol 2004 Apr;134(4):1268-82
cyclophilin J, human  EC 5.2.1.-   *Cyclophilins. Acta Crystallogr D Biol Crystallogr 2005 Mar;61(Pt 3):316-21
CypRS92 protein, Arabidopsis  EC 5.2.1.-   *Cyclophilins *Arabidopsis Proteins RNA Splicing. J Biol Chem 2004 Aug 6;279(32):33890-8
CypRS64 protein, Arabidopsis  EC 5.2.1.-   *Cyclophilins *Arabidopsis Proteins RNA Splicing. J Biol Chem 2004 Aug 6;279(32):33890-8
MOG-6 protein, C elegans  EC 5.2.1.-   *Cyclophilins *Caenorhabditis elegans Proteins. Development 2004 Jun;131(12):2935-45
cyp3 protein, S pombe  EC 5.2.1.-   *Cyclophilins *Schizosaccharomyces pombe Proteins. J Chromatogr B Analyt Technol Biomed Life Sci. 2003 Mar 25;786(1-2):81-91
cyclophilin H, human  EC 5.2.1.-   *Peptidylprolyl Isomerase Cyclophilins. J Mol Biol. 2003 Aug 1;331(1):45-56
cyp33 protein, Drosophila  EC 5.2.1.-   *Cyclophilins *Drosophila Proteins. Dev Genes Evol 2002 Apr;212(3):107-13
Moca-cyp protein, Drosophila  0   *Cyclophilins *Drosophila Proteins. J Biol Chem 2002 Oct 25;277(43):41171-82
unguilin protein, Vigna unguiculata  0   *Plant Proteins *Cyclophilins. J Protein Chem 2001 Jul;20(5):353-9
PPIL4 protein, human  EC 5.2.1.8   *RNA-Binding Proteins *Cyclophilins. Cytogenet Cell Genet 2001;95(1-2):43-7
cyclophilin 16, Onchocerca volvulus  EC 5.2.1.-   *Cyclophilins. J Biol Chem 2002 Apr 26;277(17):14925-32
Mal f 6 allergen  0   *Allergens *Cyclophilins Fungal Proteins. J Invest Dermatol 1999 Aug;113(2):156-61
cyclophilin hCyp-18  0   *Cyclophilins Peptides. FEBS Lett 2001 Sep 7;505(1):191-5
Ppil3 protein, rat  EC 5.2.1.8   *Cyclophilins. Cytogenet Cell Genet 2001;92(3-4):231-6
cyclophilin 19  0   *Cyclophilins Protozoan Proteins. FEMS Microbiol Lett 2001 Jun 12;200(1):43-7
cyclosporin A-binding protein, Leishmania donovani  0   *Cyclophilins *Protozoan Proteins. J Biol Chem 2001 Jun 1;276(22):19294-300
PPIE protein, human  EC 5.2.1.-   *Cyclophilins. Oncogene 1998 Aug 27;17(8):1019-26
PPID protein, human  EC 5.2.1.8   *Cyclophilins. Cell Stress Chaperones 1998 Jun;3(2):118-29
PPIG protein, human  EC 5.2.1.8   *Cyclophilins. Gene 1996 Nov 21;180(1-2):151-5
cyclophilin-4059  0   *Peptide Fragments *Cyclophilins. Biochemistry 1996 Dec 3;35(48):15249-55
cyclophilin D  EC 5.2.1.8   *Cyclophilins. Eur J Biochem 1996 May 15;238(1):166-72
PPIL2 protein, human  0   *Cyclophilins. Biochem J 1996 Feb 15;314(Pt 1):313-9
cyclophilin B  137497-17-7   *Cyclophilins. Cell 1993 Jun 18;73(6):1067-78
cyclophilin-S1  EC 5.2.1.-   *Cyclophilins. Biochim Biophys Acta 1991;1129(1)13
cyclophilin C  EC 5.2.1.-   *Cyclophilins Cyclosporins. Cell 1991;66(4):799

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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