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CD40 Ligand

More information in Books or onNLM PubMed
Definition: A membrane glycoprotein and differentiation antigen expressed on the surface of T-cells that binds to CD40 ANTIGENS on B-LYMPHOCYTES and induces their proliferation. Mutation of the gene for CD40 ligand is a cause of HYPER-IGM IMMUNODEFICIENCY SYNDROME, TYPE 1.     
See Also Antigens, CD40 		Other names gp39 Antigen, T Cell; T-Cell gp39 Antigen; gp39 Antigen, T-Cell; TNF Superfamily, Member 5; T-B Cell Activating Molecule; CD154 Antigen; Antigen, CD154; CD40L; Tumor Necrosis Factor Ligand Superfamily Member 5; CD154 Antigens; Antigens, CD154
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
2-(2'-(biphenyl-3-ylmethylcarbamoyl)-6,6'-bis(2-(pyrrolidin-1-ylmethyl)pyrrolidine-1-carbonyl)-4,4'-bipyridine-2-carboxamido)-2-cyclohexylacetic acid  0   *Pyridines *Pyrrolidines CD40 Ligand/antagonists & inhibitors. ACS Chem Biol. 2011 Jun 17;6(6):636-47.
ABI793 monoclonal antibody  0   *Antibodies, Monoclonal *CD40 Ligand. Transplantation. 2004 Mar 27;77(6):914-20

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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