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alpha-Tocopherol

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Definition: A natural tocopherol and one of the most potent antioxidant tocopherols. It exhibits antioxidant activity by virtue of the phenolic hydrogen on the 2H-1-benzopyran-6-ol nucleus. It has four methyl groups on the 6-chromanol nucleus. The natural d form of alpha-tocopherol is more active than its synthetic dl-alpha-tocopherol racemic mixture.  deficiency: coordinate ALPHA-TOCOPHEROL with VITAMIN E DEFICIENCY   
Pharmacological Action Vitamins; Antioxidants 		Other names alpha Tocopheryl Calcium Succinate; alpha Tocopherol Succinate; alpha Tocopherol Hemisuccinate; alpha Tocopherol Acetate; alpha Tocopherol; Calcium Succinate, alpha-Tocopheryl; alpha-Tocopheryl Calcium Succinate; alpha-Tocopherol Succinate; alpha-Tocopherol Acetate; 3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethy; alpha-Tocopherol Hemisuccinate
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
ASO3B adjuvant  0   *Polysorbates *Squalene *alpha-Tocopherol Drug Combinations. BMJ 2010;340:C2649
alpha-tocopherol succinyl dodecaethylene glycol  0   *Polyethylene Glycols alpha-Tocopherol/*analogs & derivatives. Biochem Pharmacol 2009 Dec 15;78(12):1464-74
alpha-tocopherol hexaethylene glycol succinate  0   *Polyethylene Glycols alpha-Tocopherol/*analogs & derivatives. Biochem Pharmacol 2009 Dec 15;78(12):1464-74
RRR-alpha-tocopheryloxybutyl sulfonic acid  0   *Sulfonic Acids alpha-Tocopherol/*analogs & derivatives. Clin Cancer Res 2009 Feb 1;15(3):898-906
alpha-di-tocopheryl phosphate  0   alpha-Tocopherol/*analogs & derivatives. Food Chem Toxicol 2006 Jul;44(7):916-32
alpha-tocopheryl oxalate  0   alpha-Tocopherol/*analogs & derivatives. J Nutr Sci Vitaminol (Tokyo) 2005 Dec;51(6):392-7
alpha-tocopheryl malonate  0   alpha-Tocopherol/*analogs & derivatives. J Nutr Sci Vitaminol (Tokyo) 2005 Dec;51(6):392-7
karinat  0   *Ascorbic Acid *beta Carotene *alpha-Tocopherol Garlic. Vopr Onkol 2004;50(1):81-5
polyoxyethanyl-alpha-tocopheryl sebacate  0   alpha-Tocopherol/*analogs & derivatives. Biofactors 2003;18(1-4):173-83
8a-hydroperoxy-tocopherone  141913-27-1   alpha-Tocopherol/*analogs & derivatives. Lipids 1992 Apr;27(4):289-94
1-thio-alpha-tocopherol  133869-30-4   alpha-Tocopherol/*analogs & derivatives. Free Radic Res Commun 1990;11(4-5):207
alpha-tocopherol 5-n-butyl-2-pyridinecarboxylate  85446-70-4 2-Pyridinecarboxylic acid, 5-butyl-, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-yl ester, (2R*(4R*,8R*))-(+-)  *Picolinic Acids alpha-Tocopherol/*analogs & derivatives. Nippon Yakurigaku Zasshi 1986;87(6):609
2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-6-chlorochroman  80040-98-8 2H-1-Benzopyran, 6-chloro-3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, (2R-(2R*(4R*,8R*)))  alpha-Tocopherol/*analogs & derivatives. Vopr Med Khim 1981;27(5):707
deoxy-alpha-tocopherolquinol  0   alpha-Tocopherol/*analogs & derivatives. J Biol Chem 1980;255(24):11802
alpha-tocopherol quinol  14745-36-9 2-(3-hydroxy-3,7,11,15-tetramethylhexadecyl)-3,5,6-trimethyl-1,4-benzenediol (3R-(3R*,7R*,11R*))  alpha-Tocopherol/*analogs & derivatives. J Biol Chem 1980;255(10):4447
alpha-tocopherol phosphate  38976-17-9   alpha-Tocopherol/*analogs & derivatives. J Cyclic Nucleotide Res 2(3):163;1976

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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