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BRCA2 Protein

More information in Books or onNLM PubMed
Definition: A large, nuclear protein, encoded by the BRCA2 gene (GENE, BRCA2). Mutations in this gene predispose humans to breast and ovarian cancer. The BRCA2 protein is an essential component of DNA repair pathways, suppressing the formation of gross chromosomal rearrangements. (from Genes Dev. 2000;14(11):1400-6)     
See Also Hereditary Breast and Ovarian Cancer Syndrome 		Other names Fanconi Anemia Group D1 Protein; Fanconi Anemia Group D1 Complementing Protein; FANCD1 Protein; Breast Cancer 2 Protein; BRCA2 Gene Product; Fanconi Anemia Complementation Group D1 Protein; Breast Cancer 2 Gene Product
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
brca2 protein, zebrafish  0   *BRCA2 Protein *Zebrafish Proteins. PLoS Genet. 2011 Mar;7(3) (dup#4):e1001357
BRCA2 protein, human  0   *BRCA2 Protein.
BRCA2 protein, chicken  0   *BRCA2 Protein *Avian Proteins. Oncogene 2002 Feb 7;21(7):1130-4
BRCA2 protein, mouse  0   *BRCA2 Protein Neoplasm Proteins. Proc Natl Acad Sci U S A 1997 Jun 24;94(13):6927-32

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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