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WT1 Proteins

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Definition: Isoforms encoded by the WT1 Wilms tumor suppressor gene (GENES, WILMS TUMOR) and produced by alternative splicings. They are zinc finger-containing transcription factors involved in both transactivation and repression, and are critical for normal development and function of the urogenital tract.     
See Also Genes, Wilms Tumor; Wilms Tumor 		Other names Proteins, WT1; Protein, WT1; Gene Product, WT1; WT1 Protein; WT1 Gene Product
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
WT1 (126-134), human  0   *Peptide Fragments *WT1 Proteins. Blood. 2009 Jun 25;113(26):6533-40
CMTWNQMNL peptide  0   *Oligopeptides *WT1 Proteins Cancer Vaccines. Am J Hematol 2009 May;84(5):314-5
WT1 protein, Xenopus  0   *DNA-Binding Proteins *WT1 Proteins *Xenopus Proteins Genes, Tumor Suppressor Zinc Fingers. Gene 1996 Oct 10;175(1-2):167-72

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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