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Diazepam Binding Inhibitor

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Definition: An 86-amino acid polypeptide, found in central and peripheral tissues, that displaces diazepam from the benzodiazepine recognition site on the gamma-aminobutyric acid receptor (RECEPTORS, GABA). It also binds medium- and long-chain acyl-CoA esters and serves as an acyl-CoA transporter. This peptide regulates lipid metabolism.      Other names Protein, Acyl-CoA-Binding; Peptide, DBI; Medium Chain Acyl CoA Binding Protein; Inhibitor, Diazepam Binding; Binding Inhibitor, Diazepam; Acyl CoA Binding Protein; Medium-Chain Acyl CoA-Binding Protein; EpDBI; Endozepine; DBI Peptide; Acyl-CoA-Binding Protein
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
MAA-1 protein, C elegans  0   *Diazepam Binding Inhibitor *Caenorhabditis elegans Proteins. Mol Biol Cell 2006 Oct;17(10):4318-29
diazepam binding inhibitor, pig  0   *Diazepam Binding Inhibitor. Proc Natl Acad Sci USA 1966 Jul 23; 93(15):7927-32
diazepam binding inhibitor (39-75)  153858-87-8 L-Glutamic acid, L-valyl-L-asparaginyl-L-threonyl-L-alpha-aspartyl-L-arginyl-L-prolylglycyl-L-leucyl-L-leucyl-L-alpha-aspartyl-L-leucyl-L-lysylglycyl-L-lysyl-L-alanyl-L-lysyl-L-tryptophyl-L-alpha-aspartyl-L-seryl-L-tryptophyl-L-asparaginyl-L-lysyl-L  *Peptide Fragments *Diazepam Binding Inhibitor. Regul Pept 1994 Feb 3;50(1):29-35
diazepam binding inhibitor (33-50)  0   *Neuropeptides *Peptide Fragments *Diazepam Binding Inhibitor. Adv Biochem Psychopharmacol 1990;46:51

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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