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Heterogeneous-Nuclear Ribonucleoproteins

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Definition: A family of ribonucleoproteins that were originally found as proteins bound to nascent RNA transcripts in the form of ribonucleoprotein particles. Although considered ribonucleoproteins they are primarily classified by their protein component. They are involved in a variety of processes such as packaging of RNA and RNA TRANSPORT within the nucleus. A subset of heterogeneous-nuclear ribonucleoproteins are involved in additional functions such as nucleocytoplasmic transport (ACTIVE TRANSPORT, CELL NUCLEUS) of RNA and mRNA stability in the CYTOPLASM.     
Examples Heterogeneous-Nuclear Ribonucleoprotein Group A-B; Heterogeneous-Nuclear Ribonucleoprotein Group C; Heterogeneous-Nuclear Ribonucleoprotein D; Heterogeneous-Nuclear Ribonucleoprotein Group F-H; Heterogeneous-Nuclear Ribonucleoprotein K; Heterogeneous-Nuclear Ribonucleoprotein L; Heterogeneous-Nuclear Ribonucleoprotein Group M; Heterogeneous-Nuclear Ribonucleoprotein U; RNA-Binding Protein EWS; RNA-Binding Protein FUS 		Other names Ribonucleoproteins, Heterogeneous-Nuclear; Ribonucleoprotein, Heterogeneous Nuclear; Particles, hnRNP; Nuclear Ribonucleoprotein, Heterogeneous; Heterogeneous Nuclear Ribonucleoproteins; Complexes, hnRNP; hnRNP Proteins; hnRNP Particles; hnRNP Complexes; hnRNP; Informofer; Informatin; Heterogeneous Nuclear Ribonucleoprotein
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
hnRNPUL2 protein, human  0   *Heterogeneous-Nuclear Ribonucleoproteins. Mol Cell. 2012 Feb 24;45(4):505-16.
ribonucleoprotein, PTB-binding 2, human  0   *Heterogeneous-Nuclear Ribonucleoproteins. Gene. 2012 Feb 10;493(2):243-52.
hrp36 protein, Drosophila melanogaster  0   *Drosophila Proteins *Heterogeneous-Nuclear Ribonucleoproteins. Nat Struct Mol Biol. 2007 Dec;14(2):1134-40
hnRNP-R protein, zebrafish  0   *Zebrafish Proteins *Heterogeneous-Nuclear Ribonucleoproteins. Hum Mol Genet 2010 May 15;19(10):1951-66
PCBP3 protein, human  0   *Heterogeneous-Nuclear Ribonucleoproteins. Gene 2010 Feb 1;451(1-2):23-31
40LoVe protein, Xenopus  0   *Xenopus Proteins *Heterogeneous-Nuclear Ribonucleoproteins. Dev Cell 2005 Apr;8(4):505-15
HnRNP G protein, rat  0   *Heterogeneous-Nuclear Ribonucleoproteins. J Biol Chem 2009 May 22;284(21):14303-15
hnRNPR protein, rat  0   *Heterogeneous-Nuclear Ribonucleoproteins. Neurochem Res. 2009 Jun;34(6):1083-8
samba protein, Xenopus  0   *Xenopus Proteins *Heterogeneous-Nuclear Ribonucleoproteins. Dev Dyn 2009 Jan;238(1):204-9
hnRNPLL protein, mouse  0   *Heterogeneous-Nuclear Ribonucleoproteins. Immunity 2008 Dec;29(6):863-75
Rbmx protein, Xenopus  0   *Xenopus Proteins *Heterogeneous-Nuclear Ribonucleoproteins. Dev Dyn 2008 Jul;237(7):1755-66
hnRNPQ protein, rat  0   *Heterogeneous-Nuclear Ribonucleoproteins. Biochem Biophys Res Commun. 2008 Jul 25;372(2):314-9
RBMX protein, mouse  0   *Heterogeneous-Nuclear Ribonucleoproteins. FEBS Lett 2007 Jan 23;581(2):218-22
heterogeneous-nuclear ribonucleoprotein I, mouse  0   *Heterogeneous-Nuclear Ribonucleoproteins. Mol Immunol 2007 Jan;44(4):434-42
APOBEC-1 complementation factor, rat  0   *Heterogeneous-Nuclear Ribonucleoproteins. Nucleic Acids Res 2006;34(11) (dup#2):3299-308
heterogeneous nuclear ribonucleoprotein G, human  0   *Heterogeneous-Nuclear Ribonucleoproteins. Clin Cancer Res 2006 May 15;12(10):3222-8
RBMX protein, human  0   *Heterogeneous-Nuclear Ribonucleoproteins Apoptosis. Asian J Androl 2006 Mar;8(2):213-8
Raver2 protein, mouse  0   *Heterogeneous-Nuclear Ribonucleoproteins. FEBS Lett 2005 Aug 15;579(20):4254-8
apobec-1 complementation factor, mouse  0   *Heterogeneous-Nuclear Ribonucleoproteins. Mol Cell Biol 2005 Aug;25(16):7260-9
CG9373 protein, Drosophila  0   *Drosophila Proteins *Heterogeneous-Nuclear Ribonucleoproteins. J Cell Biol 2005 Mar 28;168(7):1013-25
HNRPLL protein, human  0   *Heterogeneous-Nuclear Ribonucleoproteins. Gene 2004 Jun 9;334:113-21
Hrp48 protein, Drosophila  0   *Drosophila Proteins *Heterogeneous-Nuclear Ribonucleoproteins. J Cell Biol 1992 Jan;116(2):257-69
Hrb27C protein, Drosophila  0   *Drosophila Proteins *Heterogeneous-Nuclear Ribonucleoproteins. J Cell Biol 1992 Jan;116(2):257-69
Hnrpr protein, mouse  0   *Heterogeneous-Nuclear Ribonucleoproteins.
Syncrip protein, mouse  0   *Heterogeneous-Nuclear Ribonucleoproteins.
HNRNPUL1 protein, human  0   *Nuclear Proteins *Transcription Factors *Heterogeneous-Nuclear Ribonucleoproteins. J virol 1998 Oct;72(10):7960-71
PTBP1 protein, human  0   *Heterogeneous-Nuclear Ribonucleoproteins *Polypyrimidine Tract-Binding Protein.
ARBP protein, chicken  0   *Heterogeneous-Nuclear Ribonucleoproteins *Matrix Attachment Region Binding Proteins.
HNRNPR protein, human  0   *Heterogeneous-Nuclear Ribonucleoproteins.
SYNCRIP protein, human  0   *Heterogeneous-Nuclear Ribonucleoproteins. J Biol Chem 2000 Mar 31;275(13):9823-31; J Biol Chem 2001 Mar 30;276(13):10272-83
HNRNPG-T protein, human  0   *Heterogeneous-Nuclear Ribonucleoproteins. Hum Mol Genet. 2000 Sep 1;9(14):2117-24
Hrb87F protein, Drosophila  0   *Nuclear Proteins *Drosophila Proteins *Heterogeneous-Nuclear Ribonucleoproteins. Mol Cell Biol 1997 May;17(5):2708-15; Nucleic Acids Res 1991;19(18):4909
hrp23 protein, Chironomus tentans  0   *Insect Proteins *Heterogeneous-Nuclear Ribonucleoproteins. J Cell Biol 1998 Sep 7;142(5):1181-93
HRP45 protein, Chironomus tentans  0   *Insect Proteins *Heterogeneous-Nuclear Ribonucleoproteins RNA Splicing. Genes Dev 1996 Nov 15;10(22):2881-93
HRB98DE protein, Drosophila  0   *Drosophila Proteins *Heterogeneous-Nuclear Ribonucleoproteins. Proc Natl Acad Sci USA 1995 Mar 14;92(6):1822-5
PCBP1 protein, human  0   *Heterogeneous-Nuclear Ribonucleoproteins. Eur J Biochem 1995 Jun 1;230(2):447-53

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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