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Peptoids

More information in Books or onNLM PubMed
Definition: Polymers of N-SUBSTITUTED GLYCINES containing chiral centers at the a-position of their side chains. These oligomers lack HYDROGEN BONDING donors, preventing formation of the usual intrachain hydrogen bonds but can form helices driven by the steric influence of chiral side chains.     
Examples N-substituted Glycines 		Other names Peptoid
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
1-(3',3'-diphenylpropyl)-4-(2'-(2'',4''-dichlorophenyl)ethyl)-7-(N-aminocarbonylmethyl-N-(2-(2'',4''-dichlorophenyl)ethyl)aminocarbonyl)perhydro-1,4-diazepine-2,5-dione  0   *Azepines *Peptoids. J Med Chem 2008 Feb 14;51(3):521-9
GU40C compound  0   *Peptoids. Bioorg Med Chem Lett 2008 Nov 15;18(22):5892-4

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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