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Ephrin-A1

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Definition: An ephrin that was originally identified as the product of an early response gene induced by TUMOR NECROSIS FACTORS. It is linked to the CELL MEMBRANE via a GLYCOINOSITOL PHOSPHOLIPID MEMBRANE ANCHOR and binds EPHA2 RECEPTOR with high affinity. During embryogenesis high levels of ephrin-A1 are expressed in LUNG; KIDNEY; SALIVARY GLANDS; and INTESTINE.      Other names RPTK Ligand, Eck; Ligand, Eck; LERK 1 Protein; Ephrin A1; LERK-1 Protein; Epl1 Protein; Eck RPTK Ligand; Eck Ligand; EPLG1; B61 Secreted Protein, Endothelium; Endothelium Secreted Protein B61
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
ephrin A1-Fc fusion protein, recombinant  0   *Immunoglobulin Fc Fragments *Recombinant Fusion Proteins *Ephrin-A1. Biochem Biophys Res Commun 2004 Aug 6;320(4):1096-102

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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