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Luteinizing Hormone, beta Subunit

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Definition: The beta subunit of luteinizing hormone. It is a 15-kDa glycopolypeptide with structure similar to the beta subunit of the placental chorionic gonadatropin (CHORIONIC GONADOTROPIN, BETA SUBUNIT, HUMAN) except for the additional 31 amino acids at the C-terminal of CG-beta. Full biological activity of LH requires the non-covalently bound heterodimers of an alpha and a beta subunit. Mutation of the LHB gene causes HYPOGONADISM and infertility.      Other names Lutropin beta; LH beta; Lutropin-beta; Luteinizing Hormone, beta Polypeptide Chain; Luteinizing Hormone, beta Chain; LH-beta; Lutropin, beta Subunit; LH, beta Subunit; ICSH, beta Subunit
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Phor14-betaLH  0   *Peptide Fragments *Luteinizing Hormone, beta Subunit Prostatic Neoplasms. Reprod Biol 2001 Jul;1(1);20-32
hecate-betaLH  0   *Peptide Fragments *Luteinizing Hormone, beta Subunit Prostatic Neoplasms. Reprod Biol 2001 Jul;1(1);20-32

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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