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Pulmonary Surfactant-Associated Protein A

More information in Books or onNLM PubMed
Definition: An abundant pulmonary surfactant-associated protein that binds to a variety of lung pathogens, resulting in their opsinization. It also stimulates MACROPHAGES to undergo PHAGOCYTOSIS of microorganisms. Surfactant protein A contains a N-terminal collagen-like domain and a C-terminal lectin domain that are characteristic of members of the collectin family of proteins.  see SCR for species-specific terms; DF: SP-A PROTEIN   
Pharmacological Action Pulmonary Surfactants 		Other names SP A Protein; Pulmonary Surfactant Associated Protein A; Surfactant Protein A; SP-A Protein
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
SFTPA2 protein, human  0   *Pulmonary Surfactant-Associated Protein A.
SFTPA1 protein, human  0   *Pulmonary Surfactant-Associated Protein A.
surfactant protein A receptor  0   *Receptors, Cell Surface Pulmonary Alveoli Pulmonary Surfactant-Associated Protein A. Am J Respir Cell Mol Biol 1991;4(3):264

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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