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Receptors, Collagen

More information in Books or onNLM PubMed
Definition: Collagen receptors are cell surface receptors that modulate signal transduction between cells and the EXTRACELLULAR MATRIX. They are found in many cell types and are involved in the maintenance and regulation of cell shape and behavior, including PLATELET ACTIVATION and aggregation, through many different signaling pathways and differences in their affinities for collagen isoforms. Collagen receptors include discoidin domain receptors, INTEGRINS, and glycoprotein VI.     
Examples Integrin alpha1beta1; Integrin alpha2beta1; Integrin alpha3beta1
Other names Receptor, Collagen; Collagen Receptor; Collagen Receptors
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
VP121 protein, Vipera paleastinae  0   *Viper Venoms Receptors, Collagen/antagonists & inhibitors. Cancer Biol Ther 2009 Aug;8(15):1508-17
platelet receptor for type III collagen, human  0   *Receptors, Collagen. Histochem Cell Biol 2006 Apr;125(4):407-17
type I collagen receptor  0   *Receptors, Collagen. Arch Biochem Biophys 2002 Nov 1;407(1):10-4
integrin alpha11beta1  0   *Integrins *Receptors, Collagen. Dev Biol 2001 Sep 1;237(1):116-29

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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