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Poly(A)-Binding Proteins

More information in Books or onNLM PubMed
Definition: Proteins that bind to the 3' polyadenylated region of MRNA. When complexed with RNA the proteins serve an array of functions such as stabilizing the 3' end of RNA, promoting poly(A) synthesis and stimulating mRNA translation.  GEN; prefer specifics; note species-specific terms in SCR   
Examples Poly(A)-Binding Protein I; Poly(A)-Binding Protein II 		Other names Poly A Binding Proteins; Poly A Binding Protein; Poly(A)-Binding Protein; Poly(A)+ mRNA Binding Protein; Poly A-Binding Proteins; Poly A-Binding Protein
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Pab1 protein, S pombe  0   *Schizosaccharomyces pombe Proteins *Poly(A)-Binding Proteins. Biochem Biophys Res Commun. 2012 Jan 6;417(1):399-403
Pabp protein, Drosophila  0   *Drosophila Proteins *Poly(A)-Binding Proteins. Dev Biol 2009 Oct 1;334(1):186-97
PABPN1 protein, C elegans  0   *Caenorhabditis elegans Proteins *Poly(A)-Binding Proteins. Neurobiol Dis. 2010 Jun;38(3); 425-33
PABPC2 protein, mouse  0   *Poly(A)-Binding Proteins. Biol Reprod 2009 Mar;80(3):545-54
ePABP2 protein, human  0   *Poly(A)-Binding Proteins. J Assist Reprod Genet 2008 May;25(5):215-21
ePAB protein, human  0   *Poly(A)-Binding Proteins. J Assist Reprod Genet 2008 May;25(5):215-21
PABP55B protein, Drosophila  0   *Drosophila Proteins *Poly(A)-Binding Proteins. Dev Biol 2008 Jan 15;313(2):713-24
ePABP protein, Xenopus  0   *Poly(A)-Binding Proteins. Mol Cell Biol 2005 Mar;25(5):2060-71
UNR protein, mouse  0   *Poly(A)-Binding Proteins. Genes Dev 2004 Aug 15;18(16):2010-23
PABPC3 protein, human  0   *Poly(A)-Binding Proteins. Nucleic Acids Res 2001 May 1;29(9):1872-83
pab5 protein, Arabidopsis  0   *Arabidopsis Proteins *Poly(A)-Binding Proteins.
pab3 protein, Arabidopsis  0   *Arabidopsis Proteins *Poly(A)-Binding Proteins.
poly(A)-binding protein 1, Arabidopsis  0   *Arabidopsis Proteins *Poly(A)-Binding Proteins.
pab1 protein, S cerevisiae  0   *Saccharomyces cerevisiae Proteins *Poly(A)-Binding Proteins.
SGN1 protein, S cerevisiae  0   *Saccharomyces cerevisiae Proteins *Poly(A)-Binding Proteins.
ePAB protein, Xenopus  0   *Xenopus Proteins *Poly(A)-Binding Proteins. Genes Dev 2001 Mar 15;15(6):774-88
FabM protein, Aspergillus nidulans  0   *Fungal Proteins *Poly(A)-Binding Proteins. Genetics 1996 Dec;144(4):1463-70
PABPC4 protein, human  0   *Blood Proteins *Poly(A)-Binding Proteins. Eur J Biochem 1997 Jan 15;243(1-2):209-18
Hrb1 protein, S cerevisiae  0   *Nucleocytoplasmic Transport Proteins *Saccharomyces cerevisiae Proteins *Poly(A)-Binding Proteins. Yeast 1994 Apr;10(4):523-33
GRSF1 protein, human  0   *Poly(A)-Binding Proteins. Nucleic Acids Res 1994 Jun 25;22(12):2334-43
PUB1 protein, S cerevisiae  0   *Saccharomyces cerevisiae Proteins *Poly(A)-Binding Proteins. Mol Cell Biol 1993 Oct;13(10):6102-13
TIA1 protein, human  0   *Poly(A)-Binding Proteins. Cell 1991;67(3):629

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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