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RNA Cap-Binding Proteins

More information in Books or onNLM PubMed
Definition: Proteins that specifically bind to RNA CAPS and form nuclear cap binding protein complexes. In addition to stabilizing the 5' end of mRNAs, they serve a diverse array of functions such as enhancing mRNA transport out of the CELL NUCLEUS and regulating MRNA TRANSLATION in the CYTOPLASM.     
Examples Eukaryotic Initiation Factor-4E; Nuclear Cap-Binding Protein Complex 		Other names Cap-Binding Proteins, RNA; Cap Binding Protein Complex; Binding Proteins, Cap; Binding Protein, Cap; mRNA Cap Binding Proteins; RNA Cap Binding Proteins; Cap-Binding Protein Complex; Cap Binding Proteins; Cap Binding Protein
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
IFE-1 protein, C elegans  0   *Caenorhabditis elegans Proteins *Eukaryotic Initiation Factors RNA Cap-Binding Proteins. Mol Cells 2011 Feb;31(2):191-7
eIF(iso)4E protein, Arabidopsis  0   *Arabidopsis Proteins *Eukaryotic Initiation Factors RNA Cap-Binding Proteins. Curr Biol 2002 Jun 25;12(12):1046-51
ABH1 protein, Arabidopsis  0   *Arabidopsis Proteins *RNA Cap-Binding Proteins. Cell 2001 Aug 24;106(4):477-87
SNUPN protein, human  0   *Receptors, Cytoplasmic and Nuclear *RNA Cap-Binding Proteins. EMBO J 1998 Jul 15;17(14):4114-26
LSM1 protein, S cerevisiae  0   *Saccharomyces cerevisiae Proteins *RNA Cap-Binding Proteins. Mol Cell Biol 1998 Sep;18(9):5062-72
EIF4E2 protein, human  0   *RNA Cap-Binding Proteins Eukaryotic Initiation Factor-4E. J Biol Chem 1998 May 22;273(21):13104-9
STO1 protein, S cerevisiae  0   *Nuclear Proteins *Saccharomyces cerevisiae Proteins *RNA Cap-Binding Proteins. Genetics 1996 Apr;142(4):1095-103
DCP1 protein, S cerevisiae  EC 3.1.-   *Endoribonucleases *Saccharomyces cerevisiae Proteins *RNA Cap-Binding Proteins. Nature 1996 Aug 15;382(6592):642-6

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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