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Eukaryotic Initiation Factor-5

More information in Books or onNLM PubMed
Definition: A eukaryotic initiation factor that interacts with the 40S initiation complex and promotes the hydrolysis of the bound GTP. The hydrolysis of GTP causes the release of EUKARYOTIC INITIATION FACTOR-2 and EUKARYOTIC INITIATION FACTOR-3 from the 40S subunit and the subsequent joining of the 60S ribosomal subunit to the 40S complex to form the functional 80S initiation complex     
Pharmacological Action GTP Phosphohydrolase Activators 		Other names Peptide Initiation Factor EIF 5; Initiation Factor-5, Eukaryotic; Eukaryotic Peptide Initiation Factor 5; Eukaryotic Initiation Factor 5; Eukaryotic Peptide Initiation Factor-5; Peptide Initiation Factor EIF-5; EIF-5
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Krasavietz protein, Drosophila  0   *Drosophila Proteins *Eukaryotic Initiation Factor-5. Development 2007 May;134(9):1767-77

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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