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Dihydrouracil Dehydrogenase (NADP)

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Definition: An oxidoreductase involved in pyrimidine base degradation. It catalyzes the catabolism of THYMINE; URACIL and the chemotherapeutic drug, 5-FLUOROURACIL.     
Pharmacological Action Antineoplastic Agents 		Other names Dehydrogenase, Dihydropyrimidine; Dihydrothymine Dehydrogenase (NADP); Dihydropyrimidine Dehydrogenase

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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