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Angiostatins

More information in Books or onNLM PubMed
Definition: Circulating 38-kDa proteins that are internal peptide fragments of PLASMINOGEN. The name derives from the fact that they are potent ANGIOGENESIS INHIBITORS. Angiostatins contain four KRINGLE DOMAINS which are associated with their potent angiostatic activity.     
Pharmacological Action Angiogenesis Inhibitors; Antineoplastic Agents 		Other names Angiostatin
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
angiostatin4.5 protein, mouse  0   *Angiostatins. Biol Reprod 2011 Mar;84(3):505-13
angiostatin4.5, human  0   *Angiostatins. Cancer Res. 2004 Jan 1;64(1):162-8

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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