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Receptor, Adenosine A3

More information in Books or onNLM PubMed
Definition: A subtype of ADENOSINE RECEPTOR that is found expressed in a variety of locations including the BRAIN and endocrine tissues. The receptor is generally considered to be coupled to the GI, INHIBITORY G-PROTEIN which causes down regulation of CYCLIC AMP.      Other names Receptors, Adenosine A3; A3 Receptors, Adenosine; A3 Receptor, Adenosine; Adenosine A3 Receptor; Adenosine A3 Receptors
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
4-allyl-8-ethyl-7,8-dihydro-2-(3-methoxy-1-methyl-1H-pyrazol-5-yl)-1H-imidazo(2,1-i)purin-5(4H)-one  0   *Purines Receptor, Adenosine A3 Purinergic P1 Receptor Antagonists. J Med Chem 2011 Jul 28;54(14):5205-20
4-(2-chloro-6-(3-chlorobenzylamino)-9H-purin-9-yl)-2,3-dihydroxy-N-methylbicyclo(3.1.0)hexane-1-carboxamide  0   *Purines Receptor, Adenosine A3. Exp Eye Res 2010 Sep;91(3):425-32
N-(2-(phenyl)-8-methylpyrazolo(4,3-e)(1,2,4)triazolo(1,5-c)pyrimidin-5-yl)phenylacetamide  0   *Acetamides *Heterocyclic Compounds, 3-Ring Receptor, Adenosine A3/antagonists & inhibitors. J Med Chem 2010 Apr 22;53(8):3361-75
4'-(2-chloro-6-(3-iodobenzylamino)purine)-2',3'-O-dihydroxy-bicyclo(3.1.0)hexane  0   Adenosine/*analogs & derivatives Iodine Radioisotopes Receptor, Adenosine A3/agonists. Biochem Pharmacol 2010 Apr 1;79(7):967-73
4-benzoylamino-2-(4-methoxyphenyl)pyrido(2,3-e)-1,2,4-triazolo(4,3-a)pyrazin-1-one  0   *Heterocyclic Compounds, 3-Ring Receptor, Adenosine A3/antagonists & inhibitors. J Med Chem 2009 Apr 23;52(8):2407-19
CF 502  0   Adenosine/*analogs & derivatives Receptor, Adenosine A3/agonists. Biochem Pharmacol 2008 Aug 15;76(4):482-94
ABEA-X-BY630  0   *Boron Compounds Adenosine/*analogs & derivatives Receptor, Adenosine A3/agonists. FASEB J 2008 Mar;22(3):850-60
9-chloro-5-(4-methoxybenzoyl)amino-2-phenyl(1,2,3)triazolo(1,2-a)(1,2,4)benzotriazin-1-one  0   *Triazines *Triazoles Receptor, Adenosine A3/antagonists & inhibitors. J Med Chem 2007 Nov 15;50(23):5676-84
4-dibenzoylamino-2-(4-methoxyphenyl)pyrazoloquinoline  0   *Benzamides *Pyrazoles Receptor, Adenosine A3/antagonists & inhibitors. J Med Chem 2007 Aug 23;50(17):4061-74
4-diphenylacetylamino-2-phenylpyrazoloquinoline  0   *Benzamides *Pyrazoles Receptor, Adenosine A3/antagonists & inhibitors. J Med Chem 2007 Aug 23;50(17):4061-74
N6-methoxy-2-(4-acetylphenyl)ethynyl-5'-N-methylcarboxamidoadenosine  0   Adenosine/*analogs & derivatives Receptor, Adenosine A3/agonists. J Med Chem 2007 Mar 22;50(6):1222-30
2-chloro-N(6)-(3-iodobenzyl)-5'-N-methylcarbamoyl-4'-thioadenosine  0   *Thionucleosides Adenosine/*analogs & derivatives Receptor, Adenosine A3/agonists. Mol Cancer Ther 2006 Mar;5(3):685-92
2-(4-methoxyphenyl)-1,2,4-triazolo(1,5-a)quinoxalin-4-one  0   *Quinoxalines *Triazoles Receptor, Adenosine A3/antagonists & inhibitors. J Med Chem 2005 Dec 15;48(25):7932-45
2-chloro-N(6)-methyladenosine-5'-methyluronamide  0   Adenosine/*analogs & derivatives Receptor, Adenosine A3/agonists. Nucleosides Nucleotides Nucleic Acids 2005;24(5-7):607-9
1-benzyl-7-methyl-3-propyl-1H,8H-imidazo(2,1-f)purine-2,4-dione  0   *Purines *Imidazoles Receptor, Adenosine A3/antagonists & inhibitors. J Med Chem 2005 Jul 14;48(14):4697-701
2-(4-nitrophenyl)-1,2,4,5-tetrahydro-1,2,4-triazolo(4,3-a)quinoxaline-1,4-dione  0   *Quinoxalines *Triazoles Receptor, Adenosine A3/antagonists & inhibitors. J Med Chem 2004 Jul 1;47(14):3580-90

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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